ArticleGenetics, selection, evolution : GSE2026
Transmission of an environmental modification in quails across three generations: changes in the contribution to phenotypic variability.
Article in Genetics, selection, evolution : GSE, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundWhile epigenetic variations can contribute to shaping phenotypic diversity, it can be challenging to isolate and quantify the portion of trait variability under non-genetic influence. In this study we compared the phenotypic responses for different traits of two epilines of Japanese quails (Coturnix japonica) across three generations, using a large sample size. These epilines were built in parallel following (epi +), or not (epi -), an initial genistein ingestion in the ancestors' diet and were maintained to harbour a similar genetic structure.
resultsLinear models were fitted to extract the fraction of variance allocated to multiple factors such as family, sex and epiline. The latter was found to be significantly associated with body weight. The contribution of the epiline to phenotypic variability progressively increased from the first generation (G0) to the last (G2), leading-for example in body weight at slaughter-to an average difference for adult males and females in G2 of 9 g and 14 g respectively, between epi + offspring and controls (epi-).
conclusionsAlthough these findings suggest genetic drift, they could also reveal a possible transgenerational effect of the initial diet disruption. The analysis of other phenotypes displayed rare significant effects of the epiline. This innovative experimental design offered a unique opportunity to better understand the evolution of phenotypic variability and the parameters constituting it across three generations following or not an environmental change.
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