Evidence map›Paper›PMID 42638501›Full record

ArticleAnnals of geriatric medicine and research2026

Clinical Implications of the AWGS 2025 Sarcopenia Criteria in a Large Cohort of Community-Dwelling Thai Older Adults.

Natthaphon Ubonsutvanich, Rapas Samalapa, Thanyaporn Hengpongthorn, Chawalya Angsuwatjarakorn, Aisawan Petchlorlian, Bhorn-Ake Manasvanich, Sivarat Ratthanasathian, Kearkiat Praditpornsilpa

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Article in Annals of geriatric medicine and research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Natthaphon UbonsutvanichDivision of Geriatric Medicine, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. natthaphon.u@chula.ac.th.
Rapas SamalapaDivision of Geriatric Medicine, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Thanyaporn HengpongthornGeriatric Excellence Center, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.
Chawalya AngsuwatjarakornDivision of Geriatric Medicine, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Aisawan PetchlorlianDivision of Geriatric Medicine, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Bhorn-Ake ManasvanichGeriatric Excellence Center, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.
Sivarat RatthanasathianDepartment of Urban Medicine, Faculty of Medicine, Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Kearkiat PraditpornsilpaGeriatric Excellence Center, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Asian Working Group for Sarcopenia (AWGS) 2025 criteria introduced revised age-specific cutoffs and appendicular skeletal muscle mass adjusted for body mass index (ASM/ BMI) as an alternative muscle mass index. We evaluated their effects on sarcopenia classification among Thai older adults.

methodsThis cross-sectional study included 8,073 community-dwelling adults aged ≥60 years attending a tertiary geriatric outpatient clinic. Low muscle mass and sarcopenia were classified using AWGS 2019 and 2025. Discordant ASM/height²- and ASM/BMIbased phenotypes were characterized, and age- and sex-adjusted associations with handgrip strength and gait speed were examined.

resultsLow muscle mass prevalence increased from 43.2% under AWGS 2019 to 44.6% after applying the revised AWGS 2025 ASM/height² cutoffs and to 51.4% after including ASM/BMI. Sarcopenia prevalence increased from 15.1% to 17.5% and 19.7%, respectively. ASM/BMI identified 547 additional participants with low muscle mass. Participants with isolated low ASM/BMI had greater overall and central adiposity than those with isolated low ASM/height². ASM/height² was positively associated with handgrip strength (standardized β=0.262, p<0.001), whereas ASM/BMI was positively associated with gait speed (standardized β=0.122, p<0.001). Neither index was consistently superior across outcomes.

conclusionAWGS 2025 broadened low muscle mass and sarcopenia classification through revised age-specific cutoffs and ASM/BMI, which identified a complementary adiposity-related phenotype.

Indexed as

Independent LivingSarcopeniaAgedAged, 80 and overBody Mass IndexCross-Sectional StudiesFemaleGeriatric AssessmentHand StrengthHumansMaleMiddle AgedMuscle, SkeletalPrevalenceThailandWalking SpeedAgedDiagnosisSarcopenia

Identifiers

PMID42638501
PMCPMC13639527

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.