Evidence map›Paper›PMID 42642402›Full record

ArticleNature communications2026

Two telomere-to-telomere Nelumbo genome assemblies reveal domestication history and empower precision breeding.

Heng Sun, Jia Xin, Yuye Yu, Gangqiang Dong, Juan Liu, Xianbao Deng, Yanyan Su, Heyun Song, Ruirui Li, Dong Yang and 3 more

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Heng Sun *State Key Laboratory of Plant Diversity and Specialty Crops, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, China.ORCID http://orcid.org/0000-0002-5790-0662
Jia Xin *State Key Laboratory of Plant Diversity and Specialty Crops, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, China.
Yuye Yu *Tianjin Bio Huaxing Gene Technology Co. Ltd, Tianjin, China.
Gangqiang Dong *Amway (China) Botanical R&D Centre, Wuxi, China.
Juan LiuState Key Laboratory of Plant Diversity and Specialty Crops, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, China.
Xianbao DengState Key Laboratory of Plant Diversity and Specialty Crops, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, China.
Yanyan SuAmway (China) Botanical R&D Centre, Wuxi, China.
Heyun SongCollege of Life Sciences, Xinyang Normal University, Xinyang, China.
Ruirui LiState Key Laboratory of Plant Diversity and Specialty Crops, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, China.
Dong YangState Key Laboratory of Plant Diversity and Specialty Crops, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, China. yangdong@wbgcas.cn.ORCID http://orcid.org/0009-0004-9766-3106
Qiqi LiangTianjin Bio Huaxing Gene Technology Co. Ltd, Tianjin, China. liangqiqi@biohuaxing.com.
Shuangxia JinNational Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, China. jsx@mail.hzau.edu.cn.ORCID http://orcid.org/0000-0002-1495-9154
Mei YangState Key Laboratory of Plant Diversity and Specialty Crops, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, China. yangmei815815@wbgcas.cn.ORCID http://orcid.org/0000-0002-3629-6371

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32400219Natural Science Foundation of Hubei Province (Hubei Provincial Natural Science Foundation) JCZRJQ202400159
6 · The paper itself

Abstract

Lotus (Nelumbo) is an ancient aquatic plant of major ecological, economic, and cultural importance, yet its genomic architecture and domestication history remain incompletely resolved. Here, we generate telomere-to-telomere reference genomes for the two extant species, Asian lotus (N. nucifera) and American lotus (N. lutea). Comparative genomics analysis reveals divergence in centromeric regions and chromosomal structural variation between the two species. Population analysis of 832 globally distributed lotus accessions supports tropical Asia as the primary dispersal cradle of Asian lotus. We detect historical introgression events contributing to modern cultivated gene pools, and identify key loci regulating flower color variation and rhizome enlargement. To support research and breeding, we develop the Nelumbo Multi-omics Genome Platform (NMGP; http://182.92.235.125:18888/lotus/home/ ), integrating multi-omics data with a Pearson correlation-weighted Fusion of machine learning Models for Genomic Prediction (PFMGP) framework. These resources provide foundation for studying lotus evolution and genome-informed breeding.

Indexed as

DomesticationGenome, PlantNelumboPlant BreedingTelomereGenomics

Identifiers

PMID42642402
PMCPMC13507216

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.