Evidence map›Paper›PMID 42642647›Full record

ArticleMikrochimica acta2026

Zinc-doped carbon dots for hypochlorite ultrasensitive determination: from aqueous monitoring to live-cells imaging.

Mingdi Yu, Mengxu Si, Ningyun Cai, Tianfei Xing, Yan Li, Shushu Ding, Ding-Yi Fu

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mingdi Yu *Nantong Key Laboratory of Small Molecular Drug Innovation, School of Pharmacy, Nantong University, Nantong, 226001, China.
Mengxu Si *Nantong Key Laboratory of Small Molecular Drug Innovation, School of Pharmacy, Nantong University, Nantong, 226001, China.
Ningyun CaiNantong Key Laboratory of Small Molecular Drug Innovation, School of Pharmacy, Nantong University, Nantong, 226001, China.
Tianfei XingNantong Key Laboratory of Small Molecular Drug Innovation, School of Pharmacy, Nantong University, Nantong, 226001, China.
Yan LiNantong Key Laboratory of Small Molecular Drug Innovation, School of Pharmacy, Nantong University, Nantong, 226001, China.
Shushu DingNantong Key Laboratory of Small Molecular Drug Innovation, School of Pharmacy, Nantong University, Nantong, 226001, China. ssding@ntu.edu.cn.
Ding-Yi FuNantong Key Laboratory of Small Molecular Drug Innovation, School of Pharmacy, Nantong University, Nantong, 226001, China. fudingyi@ntu.edu.cn.ORCID https://orcid.org/0000-0001-5690-2327

Funding

China Postdoctoral Science Foundation 2023M731817Large Instruments Open Foundation of Nantong University KFJN2465Nantong University Students' innovation and entrepreneurship training program 2025146Natural Science Foundation of the Jiangsu Higher Education Institutions of China 24KJD150004Natural Science Fund of Jiangsu Province in China BK20200972Postgraduate Research & Practice Innovation Program of Jiangsu Province SJCX24_2075
6 · The paper itself

Abstract

To overcome the limitations of conventional detection methods for Hypochlorite (ClO⁻), bright blue-emitting zinc-doped carbon dots (Zn-CDs) were constructed via a streamlined and rapid hydrothermal method (within 2 h). The Zn-CDs possessed excellent water dispersibility and physicochemical stability with a quantum yield (QY) of 10.05%. Based on the Zn-O coordination structure could provide specific binding sites for ClO⁻, the Zn-CDs as fluorescent probes enabled ultrasensitive and selective detection of ClO⁻ in range of 0.1-50 µM with an exceptionally low limit of detection (LOD) of 8.14 nM. Mechanistic investigations revealed that the fluorescence quenching was attributed to surface oxidation and subsequent electron transfer. Furthermore, the Zn-CDs demonstrated excellent biocompatibility with negligible cytotoxicity and were successfully employed for intracellular fluorescence imaging of both exogenous and endogenous ClO⁻. These finding established the developed Zn-CDs as a powerful and practical analytical platform for environmental water quality monitoring and precision biomedical diagnostics.

Indexed as

Carbon Quantum DotsFluorescent DyesHypochlorous AcidZincCarbonFluorescent Chemosensor CompoundsHeLa CellsHumansLimit of DetectionMicroscopy, FluorescenceOptical ImagingSpectrometry, FluorescenceWaterCarbonFluorescent Chemosensor CompoundsFluorescent DyesHypochlorous AcidWaterZincEnvironmental monitoringFluorescence probeHypochlorite detectionIntracellular imagingZinc-doped carbon dots

Identifiers

PMID42642647

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.