ArticleVeterinary research forum : an international quarterly journal2026
Efficacy of autologous, homologous, and heterologous blood serums in healing of chemically induced corneal ulcers in dogs: a clinical and ultrasonographic study.
Article in Veterinary research forum : an international quarterly journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Corneal ulcers, particularly from alkaline chemical injuries, are a leading ocular complication in animals, accounting for about 20.00% of emergency referrals. These burns damage the conjunctiva and cornea, causing deep ulcers, potential perforation, delayed healing, infections and blindness. Prompt treatment is crucial to accelerate healing and minimize complications like permanent opacity. This study compared the efficacy of blood serums (autologous, homologous, and heterologous) against standard treatment (N-acetylcysteine and ciprofloxacin eye drops) and a control group (Normal saline) in treating induced corneal ulcers in five groups consisting of 10 healthy mixed-breed female dogs. Ulcers were created using 3.00 M sodium hydroxide-soaked filter paper on both eyes. Evaluations on 1, 7, 14, and 21 days assessed quantitative parameters (Total corneal and stromal thickness, ulcer diameter) and qualitative symptoms (photophobia, blepharospasm, discharge, congestion, edema, neovascularization, opacity)
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