Evidence map›Paper›PMID 42643987›Full record

ArticleFrontiers in toxicology2026

Neurodevelopmental outcomes relevant to autism in juvenile mice exposed to PCB 11 in the maternal diet throughout gestation and lactation.

Rebecca J Wilson, Harmanpreet K Panesar, Ilknur Dursun, Rosalia Mendieta, Peter M Andrew, Xueshu Li, Hans-Joachim Lehmler, Pamela J Lein

Abstract read
In one paragraph

Article in Frontiers in toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rebecca J WilsonDepartment of Molecular Biosciences, University of California Davis, Davis, CA, United States.
Harmanpreet K PanesarDepartment of Molecular Biosciences, University of California Davis, Davis, CA, United States.
Ilknur DursunDepartment of Molecular Biosciences, University of California Davis, Davis, CA, United States.
Rosalia MendietaDepartment of Molecular Biosciences, University of California Davis, Davis, CA, United States.
Peter M AndrewDepartment of Molecular Biosciences, University of California Davis, Davis, CA, United States.
Xueshu LiDepartment of Occupational and Environmental Health, University of Iowa, Iowa City, IA, United States.
Hans-Joachim LehmlerDepartment of Occupational and Environmental Health, University of Iowa, Iowa City, IA, United States.
Pamela J LeinDepartment of Molecular Biosciences, University of California Davis, Davis, CA, United States.

Funding

Training CoreP42ES013661 · NIEHS · UNIVERSITY OF IOWA · PI HANS-JOACHIM LEHMLER · 2006 to 2026
$60.3M
UC Davis Environmental Health Sciences Core CenterP30ES023513 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Irva Hertz-Picciotto · 2015 to 2026
$26.0M
Molecular and Cellular Basis of PCB Developmental Neurotoxicity: ViCTER supplementR01ES014901 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HANS-JOACHIM LEHMLER, Pamela J Lein · 2009 to 2026
$9.3M
ENVIRONMENTAL TOXICOLOGYT32ES007059 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI Laura S Van Winkle · 1985 to 2026
$7.9M
PCB-mediated dysbiosis of the gut microbiome: A missing link in PCB-mediated neurodevelopmental disorders?R01ES031098 · NIEHS · UNIVERSITY OF IOWA · PI CUI, JULIA YUE, LEHMLER, HANS-JOACHIM · 2020 to 2024
$3.1M
NIEHS NIH HHS P30 ES023513NIEHS NIH HHS P42 ES013661NIEHS NIH HHS R01 ES014901NIEHS NIH HHS R01 ES031098NIEHS NIH HHS T32 ES007059
6 · The paper itself

Abstract

Polychlorinated biphenyls (PCBs) pose a significant risk to the developing human brain, and recent epidemiological data suggest PCBs increase the risk and/or severity of neurodevelopmental disorders (NDD), including autism spectrum disorder (autism). Experimental animal studies confirm that PCBs disrupt neurodevelopment, resulting in behavioral deficits. Historically, research on the developmental neurotoxicity of PCBs has focused on the higher-chlorinated PCBs found in legacy commercial mixtures; however, lower-chlorinated PCBs (LC-PCBs), including congeners not present in commercial mixtures, predominate in contemporary human exposures. Previous

Indexed as

apoptosisdendritic arborizationdevelopmental neurotoxicityglial reactivityneurodevelopmental disordersneurogenesispolychlorinated biphenyls

Identifiers

PMID42643987
PMCPMC13506163

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.