In one paragraphArticle in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Gizaw Mamo GebeyehuInstitute of Biochemistry and Medical Chemistry, Medical School, University of Pecs, 7624 Pecs, Hungary.ORCID 0000-0003-4960-5759 Milorad ZjalicDepartment of Medical Biology and Genetics, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia.ORCID 0000-0003-4076-2942 Rita BognárInstitute of Biochemistry and Medical Chemistry, Medical School, University of Pecs, 7624 Pecs, Hungary.
Benjámin FarkasInstitute of Biochemistry and Medical Chemistry, Medical School, University of Pecs, 7624 Pecs, Hungary.
Shima RashidianiInstitute of Physiology, Medical School, University of Pecs, 7624 Pecs, Hungary.
Tibor Z JánosiNano-Bio-Imaging Core Facility, University of Pecs, 7624 Pecs, Hungary.
Péter UrbánHungarian Centre for Genomics and Bioinformatics, Szentágothai Research Centre, University of Pecs, 7624 Pecs, Hungary.ORCID 0000-0003-4043-3428 József KunHungarian Centre for Genomics and Bioinformatics, Szentágothai Research Centre, University of Pecs, 7624 Pecs, Hungary.ORCID 0000-0001-9607-305X Attila GyeneseiHungarian Centre for Genomics and Bioinformatics, Szentágothai Research Centre, University of Pecs, 7624 Pecs, Hungary.
Marianna PapInstitute of Biochemistry and Medical Chemistry, Medical School, University of Pecs, 7624 Pecs, Hungary.ORCID 0009-0003-1220-8239 Željko DebeljakDepartment of Pharmacology, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia.
Marija HefferDepartment of Medical Biology and Genetics, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia.ORCID 0000-0001-6770-7359 Tibor A RauchInstitute of Biochemistry and Medical Chemistry, Medical School, University of Pecs, 7624 Pecs, Hungary.
Funding
National Research, Development and Innovation Office K131588
6 · The paper itselfAbstract
Exosomes carry bioactive macromolecules driving sepsis pathogenesis, but the mechanisms underlying macrophage-to-hepatocyte communication during systemic inflammation remain poorly understood. We investigated how sepsis-induced macrophage exosomes are involved in remote intercellular crosstalk with hepatic cells via transcription factor-encoding mRNA cargo. Human monocytic THP-1 macrophages were stimulated with lipopolysaccharide (LPS), followed by exosome isolation, recipient cell uptake verification, and high-throughput RNA sequencing cargo analysis. To functionally reconstruct downstream signaling in recipient cells, exosome-enriched
Indexed as
Epigenesis, GeneticExosomesHepatocytesHistonesJumonji Domain-Containing Histone DemethylasesMafB Transcription FactorMicroRNAsPolycomb Repressive Complex 2SepsisHep G2 CellsHumansMacrophagesRNA, MessengerTHP-1 CellsHistonesJARID2 protein, humanJumonji Domain-Containing Histone DemethylasesMAFB protein, humanMafB Transcription FactorMicroRNAsMIRN155 microRNA, humanPolycomb Repressive Complex 2RNA, MessengerexosomeH3F3Aintercellular communicationJarid2MAFBmiRNA155
Identifiers
PMID42645209
PMCPMC13511736
What Socratic holds
Textmetadata
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