In one paragraphArticle in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Birthe Katrin Alexandra LangeDepartment of Neuropediatrics, Charité-University Medical Center Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.ORCID 0000-0001-8538-7344 Ioanna PolydorouDepartment of Neuropediatrics, Charité-University Medical Center Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
Viktoriia HurynBerlin Institute for Medical Systems Biology (BIMSB), Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Hannoversche Str. 28, 10115 Berlin, Germany.ORCID 0009-0009-1691-4919 Angelina M GeorgievaNeuroCure Cluster of Excellence, Charité-University Medical Center Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117 Berlin, Germany.ORCID 0000-0002-3215-427X Shanshan YouNeuroCure Cluster of Excellence, Charité-University Medical Center Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Thomas MüllerNeuroCure Cluster of Excellence, Charité-University Medical Center Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Susanne Morales-GonzalezDepartment of Neuropediatrics, Charité-University Medical Center Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.ORCID 0000-0001-7279-2092 Bettina BrandtIntegrative Biomedicine, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin, Germany.
Carmen BirchmeierNeuroCure Cluster of Excellence, Charité-University Medical Center Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117 Berlin, Germany.ORCID 0000-0002-2041-8872 Helge AmthorU1179 Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), 78180 Montigny-le-Bretonneux, France.
Markus SchuelkeDepartment of Neuropediatrics, Charité-University Medical Center Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.ORCID 0000-0003-2824-3891 Funding
Deutsche Forschungsgemeinschaft EXC2049-390688087Deutsche Forschungsgemeinschaft FOR2841; 400728090Deutsche Forschungsgemeinschaft GRK 1631: MyoGrad - International Research Training Group for Myology
6 · The paper itselfAbstract
Muscle stem cells (MuSCs) are the cellular source for the generation and regeneration of skeletal muscle. Proper muscle growth requires precise control over the differentiation and self-renewal of MuSCs. Signaling systems, such as bone morphogenetic proteins (BMPs) and Notch, suppress the myogenic differentiation of MuSCs. This allows the expansion of the progenitor pool necessary for muscle growth. To better understand the molecular mechanisms and target genes of BMPs during myogenesis, we examined the response of adult mouse MuSCs to BMP6. BMP6 stimulation of freshly isolated MuSCs suppressed myogenic differentiation. Short-term stimulation (one hour) rapidly increased the expression of classical BMP target genes, such as
Indexed as
Adult Stem CellsBone Morphogenetic Protein 6Bone Morphogenetic ProteinsReceptors, NotchSignal TransductionAnimalsCell DifferentiationMiceMuscle DevelopmentMuscle, SkeletalBone Morphogenetic Protein 6Bone Morphogenetic ProteinsReceptors, Notchadult muscle stem cellbone morphogenetic proteinCUT&TagmouseNotch pathwaypSMAD1/5/9RNA-sequencingSMAD4transcription factor binding site
Identifiers
PMID42645218
PMCPMC13511064
What Socratic holds
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