ArticleNanomaterials (Basel, Switzerland)2026
Mn Doping Enhances the Antibacterial, Antibiofilm and Anti-Virulence Activity of ZnO Nanoparticles.
Article in Nanomaterials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The modulation of ZnO physicochemical properties through Mn doping represents a promising strategy for the development of multifunctional nanomaterials with enhanced biological performance. In this study, we investigate how the nominal Mn concentration influences both the physicochemical properties and antibacterial, antibiofilm, and anti-virulence activities of ZnO nanoparticles (NPs). Mn-doped ZnO nanoparticles containing nominal Mn from 2.5 to 10 mol% were synthesized through a simple wet-chemical approach and characterized by UV-Vis, Raman, TEM, EDX, and EELS analyses. The resulting ZnO-based NPs showed average dimensions of 3.7-4.8 nm, while increasing Mn incorporation produced measurable changes in optical response and morphology of nanoparticles. Antibacterial activity was evaluated against Gram-positive and Gram-negative bacterial models by assessing planktonic growth inhibition, biofilm formation, and pyocyanin production. The sample with the highest Mn amount (Mn
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