Evidence map›Paper›PMID 42646948›Full record

ReviewToxics2026

Genotoxic, Cytotoxic, and Physiological Effects of Nano- and Microplastics in Invertebrate Model Organisms: Mechanistic Integration, Adverse Outcome Pathways, and Multi-Omics Perspectives.

Ahmet Ali Berber, Cansu Akbulut

Abstract readReview
In one paragraph

Review in Toxics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ahmet Ali BerberVocational School of Health Services, Çanakkale Onsekiz Mart University, 17100 Canakkale, Türkiye.ORCID 0000-0002-2036-6929
Cansu AkbulutDepartment of Biology, Faculty of Science, Sakarya University, 54050 Sakarya, Türkiye.ORCID 0000-0003-4333-7669

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nano- (NPs, <1 µm) and microplastics (MPs, 1 µm-5 mm) are ubiquitous contaminants whose toxicity to invertebrates carries implications at the individual scale and (although not yet quantitatively validated) at the population scale. This semi-systematic narrative review organizes available evidence within an adverse outcome pathway (AOP) framework, linking primary molecular initiating events (MIEs) to adverse outcomes while flagging evidence strength at each step. It involves a structured synthesis that applies selected PRISMA 2020 transparency principles, namely disclosed databases, a priori eligibility criteria, and explicit harvest and de-duplication counts, but does not attempt the exhaustive paired screening, formal risk-of-bias scoring, or quantitative meta-analysis of a full systematic review; this design was chosen because the marked heterogeneity of particle physicochemistry, exposure regimes, and endpoint metrics across the available literature makes pooled statistical synthesis premature. Evidence is appraised across

Indexed as

adverse outcome pathwayepigenetic toxicitygenotoxicityinvertebratemicroplasticsmulti-omicsnanoplasticsoxidative stress

Identifiers

PMID42646948
PMCPMC13517137

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.