Evidence map›Paper›PMID 42649519›Full record

ArticleChinese medicine2026

ShenNongDiet: a medicine diet recommendation system based on graph-semantic hybrid retrieval and evidence constraint generation.

Xiangying Yan, Zhuang Guo, Na Lin, Yanqiong Zhang

Abstract read
In one paragraph

Article in Chinese medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Xiangying Yan *State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No. 16, Nanxiaojie, Dongzhimennei, Beijing, 100700, China.
Zhuang Guo *State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No. 16, Nanxiaojie, Dongzhimennei, Beijing, 100700, China.
Na LinState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No. 16, Nanxiaojie, Dongzhimennei, Beijing, 100700, China.
Yanqiong ZhangState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No. 16, Nanxiaojie, Dongzhimennei, Beijing, 100700, China. yqzhang@icmm.ac.cn.ORCID https://orcid.org/0000-0002-9358-111X

Funding

CACMS Innovation Fund CI2024E003KC-10, CI2026A03801, and CI2023E001TS06Fundamental Research Funds for the Central Public Welfare Research Institutes ZXKT25035National Key Research and Development Program of China 2024YFC3505900, 2024YFC3505904
6 · The paper itself

Abstract

backgroundMedicinal diet, a core practice in Traditional Chinese medicine (TCM) rooted in the principle of "medicine and food homology", offers potential for chronic disease management and sub-health regulation. However, the broader adoption is constrained by fragmented knowledge, poor personalization, and safety risks arising from improper ingredient combinations or constitution-therapy mismatches.

objectiveWe developed and validated ShenNongDiet, a knowledge graph (KG) and retrieval-augmented generation (RAG) system for TCM dietary recommendation that explicitly models constitution suitability and ingredient contraindications.

methodsA Neo4j KG was constructed from the "Guoyi Jinghua Yao Shan" book series encompassing 3376 medicinal diets, 2110 ingredients, 1176 effects, 1122 population groups, 1078 symptoms, 459 diseases, 38,669 relationships. The system integrates dual-pathway retrieval (symbolic reasoning from KG + dense vector search using Qwen3-embedding-8B), RAG-based evidence packaging, and Low-Rank Adaptation (LoRA) fine-tuning of Qwen3-8B on 8509 evidence-constrained instruction samples to reduce the risk of the model generating unsupported content. A multi-scenario test set was constructed to evaluate system effectiveness and robustness.

resultsShenNongDiet achieved Hit@1, Hit@3, and Hit@5 of 84.00%, 90.00%, and 92.67% respectively, with a Mean Reciprocal Rank (MRR) of 0.8778. RAGAs evaluation yielded a faithfulness score of 0.831 and context recall of 0.526. Expert human evaluation further confirmed the system's strong performance in recommendation accuracy, evidence relevance, and generation faithfulness. Ablation experiments confirmed that the hybrid architecture significantly outperformed every single retrieval channel (P < 0.001), validating the complementary benefit of the symbolic and semantic retrieval.

conclusionThis study systematically constructs an explicit-semantics knowledge model of TCM medicinal diet and integrates KG reasoning with language model generation under evidence constraints. ShenNongDiet offers an expandable and safety-constrained solution for intelligent dietary services, facilitating the digital preservation of traditional dietary culture and artificial intelligence-driven personalized health management.

Indexed as

Evidence constraintsKnowledge graphLoRA fine-tuningRetrieval-augmented generationTraditional Chinese medicine diet

Identifiers

PMID42649519
PMCPMC13508355

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.