Evidence map›Paper›PMID 42649525›Full record

ArticleTropical medicine and health2026

Global research landscape of natural medicines for lower urinary tract symptoms: bibliometric and clinical trial analysis.

Qi Xiong, Lin Chen, Jin Yang, Qiuxia Ding, Yafei Yang

Abstract read
In one paragraph

Article in Tropical medicine and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qi Xiong *Department of Clinical Medicine, North Sichuan Medical College, Nanchong, 637000, China.ORCID http://orcid.org/0009-0008-7742-3577
Lin Chen *Department of Urology, Clinical Medical College & Affiliated Hospital of Chengdu University, Chengdu University, Chengdu, 610106, Sichuan, China.ORCID http://orcid.org/0000-0002-0109-2651
Jin YangDepartment of Urology, Clinical Medical College & Affiliated Hospital of Chengdu University, Chengdu University, Chengdu, 610106, Sichuan, China.ORCID http://orcid.org/0000-0002-5094-7169
Qiuxia DingShenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen, 518000, China. dingqx919@163.com.
Yafei YangDepartment of Urology, The Third Affiliated Hospital of Shenzhen University (Luohu Hospital Group), Shenzhen University, Shenzhen, 518060, Guangdong, China. yangyf66@mail2.sysu.edu.cn.ORCID https://orcid.org/0000-0002-6208-8007

Funding

Chengdu Science and Technology Bureau Technology Innovation R & D Project 2024-YF05-00989-SNHealth Commission of Sichuan Province Medical Science and Technology Program 24QNMP083National Natural Science Foundation of China 82300869the 78th Batch of General Funding Projects of China Postdoctoral Science Foundation 2025M782291
6 · The paper itself

Abstract

backgroundNatural medicines have demonstrated significant therapeutic potential in the management and attenuation of lower urinary tract symptoms (LUTS). According to the Web of Science Core Collection (WoSCC), a total of 497 related articles have been published during the last 25 years. China was the most productive country, followed by India and the United States. However, the United States showed substantial influence in earlier years and contributed prominently to clinical trial activity. This study employs a systematic, visualized synthesis of bibliometric and clinical trial data to effectively delineate the research frontier and inform future directions.

methodsTo map the research landscape, a bibliometric examination was performed using a structured search query to gather relevant papers on natural medicines and urinary symptoms published over a 25-year span. The information extracted for analysis included titles, journals, authors, affiliations, citations, keywords, and a set of keywords associated with natural medicines for urinary symptoms. Furthermore, the ClinicalTrials.gov registry was utilized to evaluate the profile of trials testing natural agents against LUTS.

resultsThe bibliometric analysis included 497 publications from 78 countries and identified a total of 22,160 cited references. China produced the highest number of publications. Review of the clinical trial data indicated that most trials were conducted in phases II-IV. Research activity in this field demonstrated phased growth, accompanied by continued institutional funding.

conclusionThis analysis has traced research outcomes and transformation models regarding natural medicines in LUTS management. Clinical investigation confirms the field's evolution toward practical implementation. A central goal of present-day investigation involves delineating the pathological mechanisms of LUTS progression, defining particular common signaling routes, and producing effective clinical medications.

Indexed as

Bibliometric examinationClinical evidenceLower urinary tract symptomsNatural medicines

Identifiers

PMID42649525
PMCPMC13508210

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.