The Plant Growth Regulator Forchlorfenuron (KT-30) Drives Atherosclerosis Progression via Lipid Homeostasis Disruption: Evidence from ApoE-Deficient Mice.

Chia-Hui Chen, Po-An Hu, Chun-Sheng Chuang, Wen-Hua Chen, Hua-Yu Tang, Chiao-Po Hsu, Tzong-Shyuan Lee

Abstract read

In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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5 · Who and what money

Authors and funding

7 authors.

Chia-Hui ChenGraduate Institute and Department of Physiology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.

Po-An HuGraduate Institute and Department of Physiology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.

Chun-Sheng ChuangGraduate Institute and Department of Physiology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.

Wen-Hua ChenGraduate Institute and Department of Physiology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.

Hua-Yu TangGraduate Institute and Department of Physiology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.

Chiao-Po HsuDivision of Cardiovascular Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei 11221, Taiwan.ORCID 0000-0003-0748-0513

Tzong-Shyuan LeeGraduate Institute and Department of Physiology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.ORCID 0000-0002-9593-4062

Funding

National Science and Technology Council 106-2320-B-002-057-MY3, 106-2320-B-002-056, 106-2811-B-002-146, 112-2314-B-075-055, and 113-2314-B-075-033

6 · The paper itself

Abstract

Oxidative stress is a central driver of atherosclerosis progression, promoting lipid peroxidation, vascular inflammation, and hepatic metabolic dysfunction. Forchlorfenuron (KT-30), a cytokinin-like plant growth regulator widely used on fruits such as kiwifruit, grapes, and watermelon, has been reported to elevate serum cholesterol levels, suggesting potential atherogenic effects. However, whether KT-30 induces oxidative stress and accelerates atherosclerosis remains unknown. Here, apolipoprotein E-deficient (apoE

Indexed as

atherosclerosisdyslipidemiaforchlorfenuronhepatic steatosisKT-30NADPH oxidaseoxidative stress

Identifiers

PMID42650217

DOI10.3390/antiox15080953

PMCPMC13510049

What Socratic holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.