Evidence map›Paper›PMID 42650802›Full record

ArticleBiomolecules2026

Quercetin Activates NRF2/SLC7A11/GPX4 Signaling to Restore Mitochondrial Function Inhibit Ferroptosis Thereby Alleviating Doxorubicin-Induced Cardiotoxicity.

Jialong Liu, Lin Zhang, Zirong Wang, Yafang Qi, Yilin Wang, Juan Wang, Lin Shi, Xiaoxiao Cheng, Qianqian Yang, Yanli Bai and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jialong LiuSchool of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Lin ZhangSchool of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Zirong WangSchool of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Yafang QiSchool of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Yilin WangSchool of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Juan WangSchool of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Lin ShiSchool of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Xiaoxiao ChengSchool of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Qianqian YangSchool of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Yanli BaiSchool of Basic Medical Sciences, Gansu University of Chinese Medicine, Lanzhou 730000, China.
Dongling LiuSchool of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.

Funding

Gansu Provincial Science and Technology Department 23JR6KA028Gansu Provincial Science and Technology Department 23JRRA1203National Natural Science Foundation of China 82360790
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amino Acid Transport System y+CardiotoxicityDoxorubicinFerroptosisMitochondriaNF-E2-Related Factor 2Phospholipid Hydroperoxide Glutathione PeroxidaseQuercetinAnimalsMaleMyocytes, CardiacOxidative StressRatsRats, Sprague-DawleySignal TransductionAmino Acid Transport System y+Doxorubicinglutathione peroxidase 4, ratNfe2l2 protein, ratNF-E2-Related Factor 2Phospholipid Hydroperoxide Glutathione PeroxidaseQuercetincardiotoxicitydoxorubicinmitochondrial ferroptosismitochondrial functionmitochondrial ROSNRF2/SLC7A11/GPX4quercetin

Identifiers

PMID42650802
PMCPMC13510337

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.