Evidence map›Paper›PMID 42651746›Full record

ArticleBiology2026

Age-Associated NAD+ Decline and Mitochondrial Dysfunction Predispose Cells to a Reversible Tumor-Permissive Metabolic State.

Bibi Amina, Zainab Nasir, Rida Nasir Butt, Ashar Alban Chanan-Khan, Safee Ullah Chaudhary

Abstract read
In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bibi AminaBiomedical Informatics and Engineering Research Laboratory (BIRL), Department of Life Sciences, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences, Lahore 54792, Pakistan.
Zainab NasirBiomedical Informatics and Engineering Research Laboratory (BIRL), Department of Life Sciences, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences, Lahore 54792, Pakistan.
Rida Nasir ButtBiomedical Informatics and Engineering Research Laboratory (BIRL), Department of Life Sciences, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences, Lahore 54792, Pakistan.ORCID 0000-0001-6388-6230
Ashar Alban Chanan-KhanDepartment of Medicine, Mayo Clinic School of Medicine, Jacksonville, FL 32224, USA.
Safee Ullah ChaudharyBiomedical Informatics and Engineering Research Laboratory (BIRL), Department of Life Sciences, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences, Lahore 54792, Pakistan.ORCID 0000-0002-3758-6581

Funding

HEC 21-320SRGP/R&D/HEC/2014, 20-2269/NRPU/R&D/HEC/12/4792, 20-3629/NRPU/R&D/HEC/14/585Ignite SRG-209LUMS STG-BIO-1008, FIF-BIO-2052, FIF-BIO-0255TWAS RG 14-319 RG/ITC/AS_C
6 · The paper itself

Abstract

Age-associated mitochondrial decline reduces NAD

Indexed as

aerobic glycolysismetabolic plasticitymetabolic reprogrammingmitochondrial agingtumorigenesisWarburg effect

Identifiers

PMID42651746
PMCPMC13509939

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.