Evidence map›Paper›PMID 42651801›Full record

ArticleCurrent issues in molecular biology2026

Localized Intratumoral Ammonium Hydroxide Administration Demonstrates Changes in Tumor Architecture and Renal Response in a Murine Breast Cancer Xenograft Model.

Hemalata Deshmukh, Camille Schacherer, Kyunghoon Yeom, Alaina Rivera, Yusuff Olayiwola, Lauren Gollahon

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hemalata DeshmukhDepartment of Biological Sciences, Texas Tech University, 2500 Broadway, Lubbock, TX 79409, USA.
Camille SchachererDepartment of Biological Sciences, Texas Tech University, 2500 Broadway, Lubbock, TX 79409, USA.
Kyunghoon YeomDepartment of Biological Sciences, Texas Tech University, 2500 Broadway, Lubbock, TX 79409, USA.
Alaina RiveraDepartment of Biological Sciences, Texas Tech University, 2500 Broadway, Lubbock, TX 79409, USA.
Yusuff OlayiwolaDepartment of Biological Sciences, Texas Tech University, 2500 Broadway, Lubbock, TX 79409, USA.ORCID 0009-0007-9892-0284
Lauren GollahonDepartment of Biological Sciences, Texas Tech University, 2500 Broadway, Lubbock, TX 79409, USA.ORCID 0000-0002-1280-3359

Funding

Empirical Foods, Inc. A18‑0187‑001
6 · The paper itself

Abstract

Breast cancer remains a leading cause of cancer-related mortality worldwide, highlighting the need for novel therapeutic strategies that selectively target tumor cells while minimizing systemic toxicity. Dietary ammonium hydroxide enhancement (AHE) has previously been shown to modulate metabolic pathways in animal studies. However, its potential as a localized anticancer therapy has not been investigated. In the present study, we evaluated the antitumor efficacy and systemic safety of NH

Indexed as

ammonia transportersammonium hydroxideapoptosisbreast cancerinflammationintratumoral therapyKi-67MDA-MB-231renal safetyRHBGRHCG

Identifiers

PMID42651801
PMCPMC13511212

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.