Evidence map›Paper›PMID 42653136›Full record

ArticleInternational journal of molecular sciences2026

Impact of IL6 and IL18 Promoter Polymorphisms on Circulating Cytokine Levels, Gene Expression, and Susceptibility to Rheumatoid Arthritis.

Viktoria Vasileva, Georgi Vasilev, Mariana Ivanova, Lyuba Miteva, Irena Manolova

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Viktoria VasilevaDepartment of Molecular Biology, Immunology and Medical Genetics, Medical Faculty, Trakia University, 6000 Stara Zagora, Bulgaria.
Georgi VasilevLaboratory of Immunology, Specialized Hospital for Active Treatment of Hematological Diseases, 1A, Kliment Ohridski Blvd., 1797 Sofia, Bulgaria.ORCID 0000-0002-6314-6889
Mariana IvanovaClinic of Rheumatology, University Hospital "St. Ivan Rilski", 1612 Sofia, Bulgaria.ORCID 0000-0002-0441-3043
Lyuba MitevaDepartment of Molecular Biology, Immunology and Medical Genetics, Medical Faculty, Trakia University, 6000 Stara Zagora, Bulgaria.ORCID 0000-0002-0028-7692
Irena ManolovaDepartment of Molecular Biology, Immunology and Medical Genetics, Medical Faculty, Trakia University, 6000 Stara Zagora, Bulgaria.ORCID 0000-0002-4905-6537

Funding

Development of research and innovation at Trakia University in service of health and sustainable well-being BG-RRP-2.004-0006-C02Fund for Scientific and Mobile project from Medical Faculty at the Trakia University, Stara Zagora, Bulgaria 1/2021Fund for Scientific and Mobile project from Medical Faculty at the Trakia University, Stara Zagora, Bulgaria 3/2023
6 · The paper itself

Abstract

Our study examined the impact of

Indexed as

Arthritis, RheumatoidGenetic Predisposition to DiseaseInterleukin-18Interleukin-6Polymorphism, Single NucleotidePromoter Regions, GeneticAdultAllelesCase-Control StudiesFemaleGenotypeHumansMaleMiddle AgedRNA, MessengerIL18 protein, humanIL6 protein, humanInterleukin-18Interleukin-6RNA, Messengergene expressionIL-18IL-6rheumatoid arthritisrs1800795rs1946518

Identifiers

PMID42653136
PMCPMC13513842

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.