ArticleInternational journal of molecular sciences2026
Dynamic Changes in Serum Aquaporin-1 and Aquaporin-5 in Transient Tachypnea of the Newborn.
Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Transient tachypnea of the newborn (TTN) is a common cause of neonatal respiratory distress, yet the role of aquaporins in its pathophysiology remains unclear. We aimed to evaluate serum aquaporin-1 and aquaporin-5 levels in neonates with TTN and their association with clinical characteristics and respiratory support parameters. This prospective study included 49 neonates (27 controls, 22 with TTN). Serum aquaporin-1 and aquaporin-5 levels were measured on the first day of life (T0) in both groups and repeated on day 3 (T3) in the TTN group using an enzyme-linked immunosorbent assay. Clinical data and respiratory support requirements were recorded. Group comparisons, correlation analyses, and multivariable regression were performed. Baseline aquaporin-1 levels were lower in the TTN group than in controls (
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