Evidence map›Paper›PMID 42654146›Full record

ArticlePharmaceutics2026

Moxifloxacin-Mediated Downregulation of Intestinal P-Glycoprotein Alters the Pharmacokinetics of Dabigatran Etexilate: Mechanistic Insights in Rats and PBPK Model-Informed Dose Optimization.

Yuchen Qu, Zhuan Yang, Wen Ma, Peng Xiao, Yani Gu, Jie Pan, Xinyun Zhang, Chen Zhao, Yunli Yu

Abstract read
In one paragraph

Article in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuchen QuSchool of Pharmacy, Nanjing Medical University, Nanjing 211166, China.ORCID 0000-0002-0649-3147
Zhuan YangDepartment of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Wen MaSchool of Pharmacy, Nanjing Medical University, Nanjing 211166, China.
Peng XiaoDepartment of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Yani GuDepartment of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Jie PanDepartment of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Xinyun ZhangDepartment of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Chen ZhaoSchool of Pharmacy, Nanjing Medical University, Nanjing 211166, China.
Yunli YuDepartment of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.ORCID 0000-0002-0811-3267

Funding

Gusu Health Talent Youth Top-notch Talent Program GSWS2022040Hunan Provincial Key Laboratory of Anti-Resistance Microbial Drugs 2023TP1013Jiangsu Provincial Natural Science Major Project BM2023004Nanjing Medical University Career Development Fund NMUR20210006National Natural Science Foundation of China 82173879National Natural Science Foundation of China 82304610National Natural Science Foundation of China 82400241Natural Science Foundation of the Colleges and Universities in Jiangsu Province 23KJD350003Plateau Discipline Project for Discipline Construction of the Second Affiliated Hospital of Soochow University XKTJ-XK202406State Key Laboratory of Advanced Drug Delivery and Release Systems DSQZ-QN-20250102Suzhou Medical College-QiLu Medical Research Program of Soochow University 24QL200212The 2025 Special Research Project, Capacity Building and Continuing Education Center of the National Health Commission of China GWJJZX20251007061Wu Jieping Medical Foundation 320.6750.2025-6-26
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

dabigatran etexilatemoxifloxacinPBPKP-gpvirtual clinical trial

Identifiers

PMID42654146
PMCPMC13516782

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.