Evidence map›Paper›PMID 42654216›Full record

ReviewNutrients2026

The Lectin Pathway of Complement as a Sentinel for Nutritional and Metabolic Status: From Molecular Immunomodulation by Nutrients to Public Health Perspectives.

Tomasz Olszowski, Dariusz Chlubek

Abstract readReview
In one paragraph

Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tomasz OlszowskiDepartment of Public Health, Epidemiology and Behavioral Genetics, Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland.ORCID 0000-0003-2874-985X
Dariusz ChlubekDepartment of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland.ORCID 0000-0003-4497-4395

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lectin pathway (LP) of complement activation functions as a crucial effector of innate immunity and a homeostatic sensor operating at the intersection of systemic metabolism, nutritional status, and endothelial integrity. This review provides a comprehensive synthesis of current molecular, clinical, and epidemiological literature regarding the environmental and metabolic regulation of this pathway. First, we summarize the biophysical, structural, and stoichiometric requirements for divalent cations in fluid-phase activation and macromolecular assembly, integrating the contrasting roles of calcium (Ca

Indexed as

Complement ActivationComplement System ProteinsImmunomodulationLectinsNutrientsNutritional StatusPublic HealthAnimalsDiabetes, GestationalFemaleHumansImmunity, InnatePregnancyComplement System ProteinsLectinsdivalent cationsfat-soluble vitaminsgestational diabetes mellituslectin pathwaymicrovascular complicationsnanoplasmonic detectionnuclear receptorssomatotropic axiszinc inhibition

Identifiers

PMID42654216
PMCPMC13516026

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.