Evidence map›Paper›PMID 42655063›Full record

ArticleMicroorganisms2026

Alterations in Vaginal Microbiota Associated with Pregnancy Outcomes in Dairy Cows Revealed by 16S rRNA Gene Sequencing.

Tong Yu, Xiaoge Zhang, Qiuyu Meng, Feng Yang, Yaqi Zhang, Yujie Tang, Xiaoting Zhu, Yangguang Li, Shikun Wang, Zijing Zhang

Abstract read
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tong YuCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID 0000-0003-0434-3126
Xiaoge ZhangCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Qiuyu MengCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Feng YangCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID 0000-0003-1915-6008
Yaqi ZhangCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Yujie TangCollege of Veterinary Medicine, Northwest A&F University, Yangling 712100, China.
Xiaoting ZhuInstitute of Animal Husbandry, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China.
Yangguang LiHenan Huahuaniu Animal Husbandry Technology Co., Ltd., Xinxiang 453500, China.
Shikun WangHenan Huahuaniu Animal Husbandry Technology Co., Ltd., Xinxiang 453500, China.
Zijing ZhangInstitute of Animal Husbandry, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China.

Funding

Key Science and Technology Research Projects in Henan 242103810023National Key R&D Program of China 2024YFD1301002
6 · The paper itself

Abstract

Early embryonic loss remains a major limitation to reproductive efficiency in dairy cows, with approximately 30-40% of embryonic mortality occurring within 21 days after artificial insemination (AI), ultimately reducing conception rates and economic profitability in dairy production. Increasing evidence suggests that reproductive tract microorganisms may contribute to pregnancy establishment; however, their functions during early gestation in dairy cows remains poorly understood. In this study, 16S rRNA gene amplicon sequencing was used to characterize vaginal microbiota profiles in multiparous Holstein dairy cows at 7.5 and 21 days after AI, with comparisons performed between pregnant and non-pregnant cows. Significant differences in microbial community structure were observed between pregnancy states. At 7.5 days post-AI, distinct differences in microbial composition were detected at the phylum level, with

Indexed as

16S rRNA gene sequencingartificial inseminationearly embryonic lossmultiparous dairy cowspregnancy statusvaginal microbiota

Identifiers

PMID42655063
PMCPMC13515298

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.