ArticleFrontiers in oncology2026
Antitumor effect of alcohol extract of
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cordyceps sinensis is a well-known traditional Chinese medicine with antitumor activity. Methods: Results: IFA dose-dependently inhibited H22 cell proliferation. Flow cytometry showed that IFA induced late-stage apoptosis. RT-PCR and Western blot revealed upregulation of P53, Bax, Cyt C, and Caspase-3, and downregulation of Bcl-2, indicating activation of the P53/Bax/Bcl-2/Cyt C/Caspase-3 pathway. Conclusions: IFA inhibits HCC growth by inducing mitochondrial apoptosis via the P53 pathway and by modulating host immunity, highlighting its potential as a natural therapeutic agent for HCC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.