Evidence map›Paper›PMID 42656414›Full record

ArticleFrontiers in public health2026

Plasma metabolomic signatures of air pollution and rheumatoid arthritis risk.

Yangchang Zhang, Tian Liang, Yang Pu, Linpeng Zhou, Lingli Ding, Chengyin Li, Xun Lei, Bin Wu

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yangchang Zhang *Department of Rheumatology and Immunology, The First Affiliated Hospital of Chongqing University of Chinese Medicine, Chongqing, China.
Tian Liang *School of Public Health, Capital Medical University, Beijing, China.
Yang PuSchool of General Education, Chongqing University of Chinese Medicine, Chongqing, China.
Linpeng ZhouDepartment of Rheumatology and Immunology, The First Affiliated Hospital of Chongqing University of Chinese Medicine, Chongqing, China.
Lingli DingDepartment of Rheumatology and Immunology, The First Affiliated Hospital of Chongqing University of Chinese Medicine, Chongqing, China.
Chengyin LiDepartment of Rheumatology and Immunology, The First Affiliated Hospital of Chongqing University of Chinese Medicine, Chongqing, China.
Xun LeiSchool of Public Health, Chongqing Medical University, Chongqing, China.
Bin WuDepartment of Rheumatology and Immunology, The First Affiliated Hospital of Chongqing University of Chinese Medicine, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Ambient air pollutants have been increasingly implicated in immune-mediated disorders, yet the metabolic perturbations through which long-term exposure may contribute to rheumatoid arthritis (RA) remain insufficiently characterized. Methods: We used data from 403,332 RA-free participants in the UK Biobank cohort to investigate the associations among long-term ambient air pollution exposure, plasma metabolic signatures, and incident RA risk. Participants were followed for a median of 14.01 years. Residential annual average concentrations of PM Results: Each standard deviation increase in the Conclusion: These findings suggest that long-term air pollution exposure is associated with incident RA risk and that systemic metabolic perturbations may represent potential biological pathways underlying this association.

Indexed as

Air PollutantsAir PollutionArthritis, RheumatoidEnvironmental ExposureAgedFemaleHumansMaleMetabolomicsMiddle AgedParticulate MatterRisk FactorsUnited KingdomAir PollutantsParticulate Matterair pollutioncohortmediationmetabolismrheumatoid arthritis

Identifiers

PMID42656414
PMCPMC13506800

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.