Evidence map›Paper›PMID 42656540›Full record

ArticleFrontiers in cardiovascular medicine2026

Prognostic implications of echocardiographic and hemodynamic profiles in cirrhosis and high-output heart failure.

Satoshi Miyashita, Raquel Lamarche, Peter Oro, Roshan B Patel, Karthik V, Rana Abualsaud, Yuichiro Yano, Toshio Naito, W H Wilson Tang, Daniel Burkhoff and 2 more

Abstract read
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Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Satoshi MiyashitaDepartment of Critical Care Medicine, Cleveland Clinic, Integrated Hospital Care Institute, Cleveland, OH, United States.
Raquel LamarcheDepartment of Critical Care Medicine, Cleveland Clinic, Integrated Hospital Care Institute, Cleveland, OH, United States.
Peter OroDepartment of Internal Medicine, Cleveland Clinic Southpointe Hospital, Community Care Institute, Cleveland, OH, United States.
Roshan B PatelDepartment of Internal Medicine, Cleveland Clinic, Community Care Institute, Cleveland, OH, United States.
Karthik VDepartment of Internal Medicine, Cleveland Clinic, Community Care Institute, Cleveland, OH, United States.
Rana AbualsaudMount Sinai Hospital, Institute of Critical Care Medicine, New York, NY, United States.
Yuichiro YanoDepartment of General Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan.
Toshio NaitoDepartment of General Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan.
W H Wilson TangDepartment of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute Cleveland Clinic Foundation, Cleveland, OH, United States.
Daniel BurkhoffDivision of Heart Failure, Hemoydnamics and MCS Research, Cardiovascular Research Foundation, New York, NY, United States.
Adriano R TonelliDepartment of Critical Care Medicine, Cleveland Clinic, Integrated Hospital Care Institute, Cleveland, OH, United States.
Matthew T SiubaDepartment of Critical Care Medicine, Cleveland Clinic, Integrated Hospital Care Institute, Cleveland, OH, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Cirrhosis is a recognized cause of high-output heart failure (HOHF), yet the prognostic relevance of paired invasive hemodynamic and echocardiographic remodeling profiles in this population remains incompletely defined. Methods: We retrospectively analyzed 41 adults with cirrhosis-associated HOHF who underwent right heart catheterization between 2015 and 2023. HOHF was defined as thermodilution cardiac index (CI) ≥ 4.0 L/min/m Results: During a median follow-up of 1.66 years, 18 patients died and 21 underwent liver transplantation. Mean CI was 5.5 ± 1.2 L/min/m Discussion: In patients with cirrhosis-associated HOHF, disproportionate left atrial remodeling, elevated CI, and higher Ees were associated with mortality. These findings support further evaluation of integrated invasive hemodynamic and quantitative echocardiographic assessment for characterizing risk-related phenotypes in cirrhosis-associated HOHF.

Indexed as

cardiac indexcirrhosisechocardiogaphyheart failurehemodynamicshigh-output cardiac failureleft atria enlargementright heart catherterisation

Identifiers

PMID42656540
PMCPMC13506855

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.