Evidence map›Paper›PMID 42656743›Full record

ArticleFrontiers in surgery2026

Sarcopenia and inflammatory markers in early-stage breast cancer: a retrospective case-control study of NLR, MLR, RDW-CV, and HRR in middle-aged and elderly women.

Yu Liu, Xinyu Zhai, Zhongyu Wang, Wei Jia

Abstract read
In one paragraph

Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yu LiuHebei Medical University, Shijiazhuang, Hebei, China.
Xinyu ZhaiDepartment of Breast Surgery, Hengshui People's Hospital, Hengshui, Hebei, China.
Zhongyu WangHebei University, Baoding, Hebei, China.
Wei JiaHebei Medical University, Shijiazhuang, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the association between sarcopenia and inflammatory markers in middle-aged and elderly women with early-stage breast cancer. Methods: Data collection was performed between April 18 and April 30, 2026. We retrospectively collected data from 263 middle-aged and elderly female patients with early-stage breast cancer who were newly diagnosed and treatment-naïve in the Department of Breast Surgery at Hebei Medical University Affiliated Hengshui People's Hospital (Harrison International Peace Hospital) between 01/09/2024 and 31/01/2026. Patients were classified into the sarcopenia and non-sarcopenia groups based on the presence of concurrent sarcopenia. Baseline patient characteristics, clinical indicators, and inflammatory markers were collected. Multivariate logistic regression was used to analyze the relationship between sarcopenia and inflammatory markers. The predictive value of NLR for sarcopenia in early-stage breast cancer was evaluated using ROC curve analysis. Results: Compared with the non-sarcopenia group, the sarcopenia group were significantly older, neutrophils, RDW-CV, PLR, NLR, MLR, and were more likely to be postmenopausal ( Conclusion: An elevated NLR was independently associated with sarcopenia in middle-aged and elderly patients with early-stage breast cancer and has reference value for predicting sarcopenia in this population, which may serve as an inexpensive preliminary screening marker.

Indexed as

early-stage breast cancerfemaleinflammatory markersmiddle-aged and elderlysarcopenia

Identifiers

PMID42656743
PMCPMC13506853

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.