Evidence map›Paper›PMID 42656985›Full record

ReviewMedComm2026

Metabolism in Tumor: Mechanisms and Therapeutic Perspectives.

Jia-Chen Cheng, Yi-Xuan Hu, Xiang-Chun Huang, Shan Jiang, Jie-Lin Wang, Yang Zhao, Shuo Chen

Abstract readReview
In one paragraph

Review in MedComm, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jia-Chen ChengDepartment of Obstetrics and Gynecology Department of Gynecologic Oncology Research Office Guangzhou Medical University Guangzhou China.
Yi-Xuan HuDepartment of Obstetrics and Gynecology Department of Gynecologic Oncology Research Office Guangzhou Medical University Guangzhou China.
Xiang-Chun HuangDepartment of Obstetrics and Gynecology Department of Gynecologic Oncology Research Office Guangzhou Medical University Guangzhou China.
Shan JiangDepartment of Obstetrics and Gynecology Department of Gynecologic Oncology Research Office Guangzhou Medical University Guangzhou China.
Jie-Lin WangDepartment of Obstetrics and Gynecology Department of Gynecologic Oncology Research Office Guangzhou Medical University Guangzhou China.
Yang ZhaoCancer Hospital of Dalian University of Technology Cancer Hospital of China Medical University Liaoning Cancer Hospital & Institute Shenyang China.ORCID https://orcid.org/0000-0003-3226-8127
Shuo ChenDepartment of Obstetrics and Gynecology Department of Gynecologic Oncology Research Office Guangzhou Medical University Guangzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor metabolic reprogramming now extends far beyond the Warburg effect, spanning glycolysis, mitochondrial oxidative phosphorylation (OXPHOS), de novo lipogenesis, cholesterol biosynthesis, and fatty acid oxidation. This network is shaped by cell-intrinsic regulatory layers-transcriptional programs, histone lactylation and other posttranslational modifications, and m

Indexed as

combination immunotherapydrug resistanceHIF‐1α–glycolysishistone lactylationmetabolic plasticitynanomedicineSREBP–FASN axistumor metabolismtumor microenvironment

Identifiers

PMID42656985
PMCPMC13507715

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.