Evidence map›Paper›PMID 42657060›Full record

ArticleiScience2026

Phage-display immunoprecipitation sequencing reveals distinct antibody repertoire patterns across rural and urban populations.

Ross F Laidlaw, Gabriel Innocenti, Melanie Prinzensteiner, Thomas Vogl, Moustapha Mbow, Maria Yazdanbakhsh, Mikhael D Manurung

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ross F LaidlawLeiden University Center for Infectious Diseases (LUCID), Leiden University Medical Center, Leiden, the Netherlands.
Gabriel InnocentiCenter for Cancer Research, Medical University of Vienna, Vienna, Austria.
Melanie PrinzensteinerCenter for Cancer Research, Medical University of Vienna, Vienna, Austria.
Thomas VoglCenter for Cancer Research, Medical University of Vienna, Vienna, Austria.
Moustapha MbowDepartment of Immunology, Faculty of Medicine, Pharmacy, and Odontology, Cheikh Anta Diop University of Dakar, Dakar, Senegal.
Maria YazdanbakhshLeiden University Center for Infectious Diseases (LUCID), Leiden University Medical Center, Leiden, the Netherlands.
Mikhael D ManurungLeiden University Center for Infectious Diseases (LUCID), Leiden University Medical Center, Leiden, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Environmental microbial exposures are hypothesized to shape immune profile differences across rural and urban populations, yet evidence linking exposures to immune phenotypes remains limited. We used phage-displayed immunoprecipitation sequencing (PhIP-seq) to profile antibody repertoires against 357,192 epitopes from >700 organisms in 62 age-matched healthy adults from rural Senegal (

Indexed as

antibody repertoireimmune variationmulti-omics integrationphage-display immunoprecipitation sequencingrural-urban differences

Identifiers

PMID42657060
PMCPMC13508669

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.