ArticleThe Journal of international medical research2026
Association between vitamin D deficiency and clinical outcomes in critically ill patients: A retrospective cohort study.
Article in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
ObjectiveTo evaluate the association between vitamin D status and clinical outcomes in critically ill patients using the Medical Information Mart for Intensive Care IV database.MethodsAmong 73,181 intensive care unit admissions recorded in the MIMIC-IV database, 1221 patients whose serum 25(OH)D levels were available and who had stayed in the intensive care unit for ≥24 h were included. Patients were classified as vitamin D deficient (<20 ng/mL) or non-deficient (≥20 ng/mL). Primary outcomes were hospital mortality and length of hospital stay; secondary outcomes included intensive care unit length of hospital stay and prolonged mechanical ventilation. Multivariable linear and Cox proportional hazards regression analyses were performed after adjusting for demographic and clinical covariates.ResultsMedian patient age was 63 years, and 57% were female. Vitamin D deficiency prevalence was 46.0%. Median length of hospital stay was longer in the deficient group than in the non-deficient group (23.45 (12.29-43.84) vs. 20.15 (10.94-36.77);
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