Evidence map›Paper›PMID 42662487›Full record

ArticleCase reports in critical care2026

Multimodal Monitoring in Eclamptic Intracerebral Hemorrhage Complicated by Reversible Cerebral Vasoconstriction Syndrome (RCVS): A Case Report.

Giada Cucciolini, Marta Pillitteri, Lara Vegnuti, Francesco De Masi, Baldassare Ferro

Abstract read
In one paragraph

Article in Case reports in critical care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Giada CuccioliniDepartment of Surgical, Medical, Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy, unipi.it.ORCID https://orcid.org/0000-0001-9456-439X
Marta PillitteriAnesthesia and Critical Care Department, Azienda Toscana Nord Ovest, Livorno, Italy.ORCID https://orcid.org/0009-0005-0077-1790
Lara VegnutiAnesthesia and Critical Care Department, Azienda Toscana Nord Ovest, Livorno, Italy.ORCID https://orcid.org/0000-0003-0032-8930
Francesco De MasiDepartmental Structure of Neuroanesthesia and Intensive Care, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy, ao-pisa.toscana.it.ORCID https://orcid.org/0009-0000-6034-6044
Baldassare FerroAnesthesia and Critical Care Department, Azienda Toscana Nord Ovest, Livorno, Italy.ORCID https://orcid.org/0000-0001-9718-9943

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Eclampsia is a rare but severe obstetric condition associated with maternal morbidity and mortality. Neurological complications are rare and often compounded by systemic involvement such as HELLP syndrome and coagulopathy. In this complex setting, multimodal neuromonitoring may support individualized management. Case: A 32-year-old woman at 37 weeks' gestation presented with new-onset tonic-clonic seizures, severe hypertension, and laboratory findings consistent with HELLP syndrome and disseminated intravascular coagulation. Following emergency cesarean section, brain CT revealed a right frontal intracranial hemorrhage (ICH) with mass effect. Given the high surgical risk related to coagulopathy, conservative management was pursued after placement of an invasive intracranial pressure (ICP) monitoring. In the neuro-ICU, a multimodal monitoring strategy combining ICP waveform analysis, continuous electroencephalography, cerebral near-infrared spectroscopy, and transcranial color-coded duplex ultrasound (TCCD) guided therapy. Medical treatment successfully controlled intracranial hypertension and restored cerebral compliance. Daily TCCD examinations revealed progressively increased middle cerebral artery flow velocities, leading to early suspicion and radiological confirmation of reversible cerebral vasoconstriction syndrome (RCVS). Treatment with verapamil and levosimendan resulted in rapid normalization of Doppler velocities without systemic hypotension. Outcome: The patient showed progressive neurological recovery and was discharged to rehabilitation. After 6 months, functional outcome was favorable (modified Rankin Scale = 2). Conclusions: This case underscores the value of bedside TCCD integrated with multimodal neuromonitoring in the management of a complicated eclampsia with ICH and RCVS. Assessment of cerebral hemodynamics and perfusion may support safe conservative management in high-risk neuro-intensive care patients.

Indexed as

eclampsiaHELLPmultimodal monitoringRCVSTCCD

Identifiers

PMID42662487
PMCPMC13519953

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.