Evidence map›Paper›PMID 42662739›Full record

ArticleACS omega2026

Transporter Interactions of Methoxyflavones and Their

Min-Ji Kang, Kyeong-Ryoon Lee, Hyerim Song, Yunjin Seol, Yoon-Jee Chae

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Min-Ji KangCollege of Pharmacy, Woosuk University, Wanju 55338, Korea.
Kyeong-Ryoon LeeLaboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju 28116, Republic of Korea.ORCID https://orcid.org/0000-0003-2175-8876
Hyerim SongCollege of Pharmacy, Woosuk University, Wanju 55338, Korea.
Yunjin SeolCollege of Pharmacy, Woosuk University, Wanju 55338, Korea.
Yoon-Jee ChaeDepartment of Pharmacology, College of Medicine, Konyang University, Daejeon 35365, Republic of Korea.ORCID https://orcid.org/0000-0003-4921-4192

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flavonoids are widely consumed dietary polyphenols that modulate drug disposition via membrane transporters. Increasing attention has been paid to methoxyflavones (MeO-FLVs) because methoxylation can increase membrane permeability and metabolic stability, potentially elevating transporter-mediated drug-drug interaction risk; however, position-specific effects are poorly defined. We profiled a series of structurally related flavones (3-OH-FLV, 3-MeO-FLV, 5-MeO-FLV, 6-MeO-FLV, and 7-MeO-FLV) across major uptake and efflux transporters.

Identifiers

PMID42662739
PMCPMC13520515

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.