Trial reportIn vivo (Athens, Greece)
Pain and Analgesic Doses
Trial report in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimCytokines (CYT) are regulators of the acute phase immune response (APR) to inflammation and trauma. The purpose of this work was to assess blood level correlations of various CYTs; interleukin-18 (IL-18), IL-18 binding protein (IL-18BP), free interleukin 18 (IL-18F) PATIENTS AND
methodsBlood levels of IL-18, IL-18BP, IL-18F and five CYTs were determined and the NRS pain surveys were performed preoperatively (PRE) and postoperatively (POP).
resultsThe IL-18F blood levels correlated to IL-18 (
conclusionThis is the first report to demonstrate that postoperative IL-18F levels are significantly associated with NRS pain scores and the number of analgesic doses in patients undergoing cholecystectomy. These findings suggest that IL-18F and IL-18BP may contribute to the acute-phase immune response to surgical trauma and its relationship with postoperative pain and analgesic requirements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.