Evidence map›Paper›PMID 42669010›Full record

ReviewCureus2026

A Review of Vulvovaginal Atrophy as Part of Genitourinary Syndrome of Menopause.

Corrie DeGraffenreid, Emmanuel Amabebe

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Corrie DeGraffenreidObstetrics and Gynecology, The University of Texas Medical Branch, Galveston, USA.
Emmanuel AmabebeObstetrics and Gynecology, The University of Texas Medical Branch, Galveston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this narrative review, we evaluate and discuss current literature on the assessment of vulvovaginal atrophy as part of the genitourinary syndrome of menopause. Publications discussing clinical evaluation methods, including physical exam, cytology, pH, and symptom questionnaires, as well as laboratory evaluation through histology and genetic analysis, were reviewed. A wide variety of methods are used to clinically evaluate the signs and symptoms of atrophy; however, these tools lack consistency and validation across publications. We also appraised the pertinent publications evaluating the genetic changes in the vagina occurring with menopause and subsequent treatment. More research is needed to validate and standardize clinical evaluation techniques and to further define the genetic pathway alterations to develop targeted therapies in the future.

Indexed as

geneticsgenitourinary syndrome of menopausemenopausevaginal estrogenvulvovaginal atrophy

Identifiers

PMID42669010
PMCPMC13525835

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.