Evidence map›Paper›PMID 42670222›Full record

ArticleTherapeutic advances in respiratory disease

Small airway dysfunction in bronchiectasis patients with exercise-induced desaturation.

Chiung-Hsin Chang, Chun-Hua Wang, Chun-Yu Lin, Po-Jui Chang, Ting-Yu Lin, Shu-Min Lin, Bing-Chen Wu, Chien-Da Huang, Hung-Yu Huang, Fu-Tsai Chung and 5 more

Abstract read
In one paragraph

Article in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Chiung-Hsin ChangDepartment of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.ORCID 0000-0003-2495-6464
Chun-Hua WangDepartment of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chun-Yu LinChang Gung University College of Medicine, Taoyuan, Taiwan.ORCID 0000-0003-4165-3588
Po-Jui ChangDepartment of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Ting-Yu LinDepartment of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Shu-Min LinDepartment of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Bing-Chen WuDepartment of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chien-Da HuangDepartment of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Hung-Yu HuangDepartment of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Fu-Tsai ChungDepartment of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chang-Wei LinDepartment of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Meng-Heng HsiehDepartment of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chen-Te WuChang Gung University College of Medicine, Taoyuan, Taiwan.
Horng-Chyuan LinDepartment of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chun-Yu LoDepartment of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.ORCID 0000-0003-3864-8702

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundIn non-cystic fibrosis bronchiectasis, small airway airflow limitation is primarily driven by mucus plugging, chronic neutrophilic inflammation, and epithelial injury. These primary mechanisms lead to subsequent airway remodelling and luminal narrowing. Such functional impairment is clinically significant, as a reduced distance-saturation product (DSP) of <280 m% during the 6-minute walk test (6MWT) is associated with increased mortality.ObjectiveTo evaluate the association between small airway dysfunction (SAD), exercise-induced desaturation (EID), and impaired exercise capacity in patients with bronchiectasis.DesignA retrospective, cross-sectional study.MethodsThis retrospective study included 114 patients with bronchiectasis (non-desaturators, n = 57; desaturators, n = 57) and 53 non-bronchiectasis controls. Impulse oscillometry (IOS), spirometry, and 6MWT data were analysed. Desaturators were defined as a maximal decline in peripheral oxygen saturation (ΔSpO

Indexed as

BronchiectasisExerciseExercise ToleranceLungOxygen SaturationAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedOscillometryRetrospective StudiesSpirometryWalk Testbronchiectasisexercise-induced desaturation (EID)impulse oscillometry (IOS)six-minute walk test (6MWT)small airway dysfunction

Identifiers

PMID42670222
PMCPMC13530447

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.