Evidence map›Paper›PMID 42670629›Full record

Trial reportFASEB journal : official publication of the Federation of American Societies for Experimental Biology2026

Low Carbohydrate Availability in Energy Balance Alters Bone Turnover and Muscle Proteomic Response With Limited Endocrine Disruption.

Erick Mosquera-Lopez, Harry L Taylor, Yusuke Nishimura, Carl Langan-Evans, Sam O Shepherd, Juliette A Strauss, James P Morton, Jatin G Burniston, Jose L Areta

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Erick Mosquera-LopezResearch Institute for Sport & Exercise Sciences (RISES), Liverpool John Moores University, Liverpool, UK.ORCID https://orcid.org/0000-0002-0505-0352
Harry L TaylorResearch Institute for Sport & Exercise Sciences (RISES), Liverpool John Moores University, Liverpool, UK.ORCID https://orcid.org/0000-0002-6925-6982
Yusuke NishimuraResearch Institute for Sport & Exercise Sciences (RISES), Liverpool John Moores University, Liverpool, UK.ORCID https://orcid.org/0000-0001-8225-7675
Carl Langan-EvansResearch Institute for Sport & Exercise Sciences (RISES), Liverpool John Moores University, Liverpool, UK.ORCID https://orcid.org/0000-0003-1120-6592
Sam O ShepherdResearch Institute for Sport & Exercise Sciences (RISES), Liverpool John Moores University, Liverpool, UK.ORCID https://orcid.org/0000-0001-6292-1356
Juliette A StraussResearch Institute for Sport & Exercise Sciences (RISES), Liverpool John Moores University, Liverpool, UK.ORCID https://orcid.org/0000-0001-7175-2494
James P MortonResearch Institute for Sport & Exercise Sciences (RISES), Liverpool John Moores University, Liverpool, UK.
Jatin G BurnistonResearch Institute for Sport & Exercise Sciences (RISES), Liverpool John Moores University, Liverpool, UK.ORCID https://orcid.org/0000-0001-7303-9318
Jose L AretaResearch Institute for Sport & Exercise Sciences (RISES), Liverpool John Moores University, Liverpool, UK.ORCID https://orcid.org/0000-0001-6918-1223

Funding

Liverpool John Moores University (LJMU)
6 · The paper itself

Abstract

Training with low carbohydrate availability (LCA) has been proposed as an independent determinant of physiological perturbations commonly attributed to low energy availability (LEA) and to increase skeletal muscle oxidative machinery, yet the effects of LCA in isolation from LEA remain unclear. We examined whether short-term carbohydrate restriction under energy balance alters endocrine and metabolic markers associated with LEA and skeletal muscle proteomic response. In a randomized crossover design, eight trained males completed 4 days of either a low-carbohydrate high-fat diet (LOW; 12% carbohydrate, 69% fat, 19% protein) or a normal-carbohydrate diet (NORM; 62% carbohydrate, 19% fat, 19% protein), while undertaking daily cycloergometer exercise (15 kcal kg FFM

Indexed as

Diet, Carbohydrate-RestrictedEnergy MetabolismMuscle, SkeletalCross-Over StudiesHumansMaleProteomicsdietary periodisationenergy deficitlow‐carbohydrate high‐fat dietmuscle proteomics

Identifiers

PMID42670629
PMCPMC13527594

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.