Evidence map›Paper›PMID 42676694›Full record

ArticleMedComm2026

Ursodeoxycholic Acid Reduces Angiotensin-Converting Enzyme 2 Activity and Suppresses Cytokine Storm Syndrome in Patients With Coronavirus Disease 2019.

Zhaowei Tong, Jiawei Zhu, Jianfeng Zhong, Qi Wang, Fuchu Qian, Lili Zhao, Weihong Wang, Yuepao Cai, Kefeng Qin

Abstract read
In one paragraph

Article in MedComm, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhaowei TongDepartment of Infectious Diseases Huzhou Central Hospital The Affiliated Huzhou Hospital Zhejiang University School of Medicine Huzhou China.
Jiawei ZhuDepartment of Infectious Diseases Huzhou Central Hospital The Affiliated Huzhou Hospital Zhejiang University School of Medicine Huzhou China.
Jianfeng ZhongDepartment of Infectious Diseases Huzhou Central Hospital The Affiliated Huzhou Hospital Zhejiang University School of Medicine Huzhou China.
Qi WangDepartment of Infectious Diseases Huzhou Central Hospital The Affiliated Huzhou Hospital Zhejiang University School of Medicine Huzhou China.
Fuchu QianDepartment of Laboratory Medicine Huzhou Central Hospital Huzhou China.
Lili ZhaoDepartment of Laboratory Medicine Huzhou Central Hospital Huzhou China.
Weihong WangDepartment of Infectious Diseases Huzhou Central Hospital The Affiliated Huzhou Hospital Zhejiang University School of Medicine Huzhou China.
Yuepao CaiWenzhou University Wenzhou China.
Kefeng QinDepartment of Infectious Diseases Huzhou Central Hospital The Affiliated Huzhou Hospital Zhejiang University School of Medicine Huzhou China.ORCID https://orcid.org/0009-0006-9570-1425

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ursodeoxycholic acid (UDCA) decreases angiotensin-converting enzyme 2 (ACE2) activities by inhibiting farnesoid X receptor (FXR). To investigate the role of UDCA in decreasing SARS-CoV-2 infection and affecting COVID-19 cytokine levels, COVID-19 patients (

Indexed as

angiotensin‐converting enzyme 2coronavirus disease 2019cytokinecytokine storm syndromesevere acute respiratory syndrome coronavirus 2ursodeoxycholic acid

Identifiers

PMID42676694
PMCPMC13527531

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.