Evidence map›Paper›PMID 42678542›Full record

ReviewInternational journal of legal medicine2026

Biological matrices for determining the origin of post-mortem ethanol: Recommendations for collection and storage.

Allane Patricia Santos da Paz, Luiz Basílio Bouzas Nunez, Vanessa Jóia de Mello

Abstract readReview
PubMed Publisher
In one paragraph

Review in International journal of legal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Allane Patricia Santos da Paz *Laboratório de Pesquisa, Ensino e Extensão em Análises Clínicas (LACPEE), Institute of Biological Sciences, Universidade Federal do Pará (UFPA), Belém, PA, Brazil. allane.paz@icb.ufpa.br.ORCID http://orcid.org/0000-0001-6084-6989
Luiz Basílio Bouzas Nunez *Institute of Legal Medicine, Coordination of Forensic Autopsy Research, Renato Chaves Scientific Expertise Center, Belém, PA, Brazil.ORCID http://orcid.org/0009-0000-8507-2502
Vanessa Jóia de MelloLaboratório de Pesquisa, Ensino e Extensão em Análises Clínicas (LACPEE), Institute of Biological Sciences, Universidade Federal do Pará (UFPA), Belém, PA, Brazil.ORCID http://orcid.org/0000-0003-0359-9760

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ethanol is one of the most widely used psychoactive substances worldwide and one of the most frequently investigated substances in forensic toxicology laboratories. Choosing the most appropriate biological sample for its screening is extremely important in forensic autopsy, mainly to differentiate alcohol consumed before death from alcohol formed post-mortem, as well as to reduce the risk of ethanol loss through oxidation or metabolism. Therefore, this study presents an integrative review of recent literature on the collection, storage, and availability of biological matrices collected during forensic autopsy for detecting alcohol and its metabolites, considering the post-mortem condition and decomposition status of the body. The Scopus, Web of Science, and PubMed databases were searched, with searches limited to English-language articles from the past 10 years, excluding reviews and meta-analyses. The language and time restrictions were adopted to ensure methodological consistency, linguistic homogeneity, accessibility for an international readership, and focus on recent evidence relevant to current forensic toxicology practice. After excluding duplicates, the initial screening identified 414 articles. After analyzing the titles, abstracts, and full texts, articles with unavailable full text, incorrect study design, incorrect publication type, or off-topic content were excluded. From a detailed analysis of the 54 definitively included articles, data were collected on study objectives, main results, recommendations for collection and storage, and potential biomarkers. In general, it is recommended to analyze multiple matrix types and biomarkers, collect samples in duplicate, refrigerate or freeze them depending on the storage time, use preservatives, and provide adequate staff training. Protocols that provide greater clarity between results and more faithfully reflect real conditions are relevant to investigations and can prevent or detect alterations in ethanol levels in biological samples, thereby ensuring the validity, integrity, and traceability of evidence from its collection to its presentation in court.

Indexed as

AlcoholAnte-mortemBiomarkerEthyl glucuronideEthyl sulfate

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.