ArticleJournal of Korean biological nursing science2026
Factors associated with health-related quality of life in patients with chronic liver disease in Korea: a cross-sectional study.
Article in Journal of Korean biological nursing science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeThis study aimed to identify factors associated with health-related quality of life (HRQoL) in patients with chronic liver disease and to provide foundational data for developing intervention programs.
methodsThis cross-sectional study included 166 patients recruited from a general hospital in Jeonju, South Korea. Data were collected using structured questionnaires assessing depression, uncertainty in illness, and subjective health status and were analyzed using descriptive statistics, the independent t-test, one-way analysis of variance, Pearson correlation coefficients, and multiple regression analysis using SPSS version 23 program.
resultsThe mean HRQoL score was 3.19 ± 0.54 (range 1~5). Depression, uncertainty in illness, subjective health status, and education level were significant factors associated with HRQoL. Higher depressive symptom scores (β = -.24, p = .002) and greater uncertainty in illness (β = -.15, p = .044) were associated with lower HRQoL, whereas better subjective health status (β = .34, p < .001) and a higher education level were associated with higher HRQoL.
conclusionThese findings may inform intervention programs to improve HRQoL in patients with chronic liver disease by addressing depressive symptoms, uncertainty in illness, subjective health status, and educational needs.
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