Evidence map›Paper›PMID 42681160›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Reconstructing Tumor Dynamics: CAM-ECM Scaffolds as 3D Platforms for Ex Vivo Cancer Studies and Beyond.

Julie S Di Martino

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Julie S Di MartinoDepartment of Cell and Molecular Physiology, New York Medical College, Valhalla, NY, USA. jdimarti@nymc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This protocol presents a detailed, step-by-step method to generate three-dimensional (3D) extracellular matrix (ECM) scaffolds derived from cells cultured in fertilized chicken eggs. This innovative approach leverages the natural environment of the developing egg to produce physiologically relevant ECM structures. The resulting 3D scaffolds provide a robust platform to investigate cellular behavior in response to ECM composition and organization in an ex vivo setting. This method offers a cost-effective and scalable alternative to traditional in vitro and in vivo models to study ECM, enabling researchers to explore cell-ECM interactions with greater biological fidelity.

Indexed as

Cell Culture Techniques, Three DimensionalChorioallantoic MembraneExtracellular MatrixNeoplasmsTissue EngineeringTissue ScaffoldsAnimalsCell Culture TechniquesChick EmbryoChickensHumans3D ECM3D scaffoldCancerChicken CAM

Identifiers

PMID42681160

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.