Evidence map›Paper›PMID 42681291›Full record

ReviewBiogerontology2026

Phase-transition failure in aged skeletal muscle regeneration.

Bo Zhang, Haijiao Shi, Xiaojing Guo, Yan Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Biogerontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bo Zhang *The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China.
Haijiao Shi *Department of Cardiology, The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Xiaojing GuoSecond Clinical College, Shanxi University of Chinese Medicine, Taiyuan, China.
Yan WangThe Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China. swallow-1113@163.com.

Funding

Harbin Science and Technology Bureau Science and Technology Plan Project ZC2022ZJ004024
6 · The paper itself

Abstract

Aged skeletal muscle is impaired at every phase of post-injury repair that has been examined, with myeloid recruitment delayed and skewed in composition, debris degradation lagging behind uptake, and muscle stem cell (MuSC) activation following a conserved trajectory at delayed kinetics. Deficits inside a phase may be differences of degree that a longer window absorbs, whereas the transition between phases offers no comparable slack. Each transition is triggered by a defined switch in signal, either the fall in damage input after debris degradation, the TNF/TGF-β balance that permits fibro-adipogenic progenitor (FAP) apoptosis, or the Ly6C

Indexed as

AgingMuscle, SkeletalRegenerationAnimalsHumansAgingInflammationRegenerationSatellite cellsSkeletal muscle

Identifiers

PMID42681291

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.