ReviewAlzheimer's & dementia : the journal of the Alzheimer's Association2026
A world view: Considerations of sociocultural diversity in the study of subjective cognitive decline in Alzheimer's disease and related dementias.
Abstract readReview
In one paragraph
Review in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
52 authors.
Mark A Dubbelman *Center for Alzheimer Research and Treatment, Department of Neurology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-5708-4925
Tanisha G Hill-Jarrett *Department of Neurology, Memory and Aging Center, University of California San Francisco, San Francisco, California, USA.
Silvia ChapmanCognitive Neuroscience Division, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York, USA.
Gustavo Alves Andrade Dos SantosDepartment of Anatomy and Surgery, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Martina AzarBrown University Health, Providence, Rhode Island, USA.
Ganesh M BabulalDepartment of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0001-7966-3509
Tyler R BellDepartment of Psychiatry, University of California San Diego, San Diego, California, USA.ORCID https://orcid.org/0000-0001-5702-5995
Mark A BernardDepartment of Neurology, New York University Grossman School of Medicine, New York, New York, USA.ORCID https://orcid.org/0000-0003-2523-9782
Carolina Boza-CalvoDepartment of Neurology, New York University Grossman School of Medicine, New York, New York, USA.
Anthony Q BriggsDepartment of Neurology, New York University Grossman School of Medicine, New York, New York, USA.ORCID https://orcid.org/0000-0002-9459-5214
Omonigho Michael BubuDepartment of Neurology, New York University Grossman School of Medicine, New York, New York, USA.
Heather E CuevasSchool of Nursing, The University of Texas at Austin, Austin, Texas, USA.ORCID https://orcid.org/0000-0003-4314-6686
N Maritza DowlingSchool of Nursing, George Washington University, Washington, District of Columbia, USA.ORCID https://orcid.org/0000-0001-8642-7299
Darlingtina K EsiakaCenter for Health, Engagement, and Transformation. University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0001-9214-5677
Bernadette A FaustoCenter for Molecular & Behavioral Neuroscience, Rutgers University-Newark, Newark, New Jersey, USA.ORCID https://orcid.org/0000-0002-8412-1023
Fabricio Ferreira de OliveiraEscola Paulista de Medicina, Federal University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-8311-0859
Carol E FranzDepartment of Psychiatry, University of California San Diego, San Diego, California, USA.
Joyla A FurlanoDepartment of Family Medicine, Queen's University, Kingston, Ontario, Canada.
Christopher Gonzalez-CoronaRosalind Franklin University of Medicine and Science, Chicago, Illinois, USA.
M Aaron GuestCenter for Innovation in Healthy and Resilient Aging, Edson College of Nursing and Health Innovation, Arizona State University, Phoenix, Arizona, USA.ORCID https://orcid.org/0000-0001-7356-3734
Veer Bala GuptaSchool of Medicine, Deakin University, Geelong, Victoria, Australia.
Vivek K GuptaFaculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales, Australia.
Daija JacksonCollege of Graduate and Professional Studies, The Chicago School, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0002-0966-9507
Jillian L JoyceLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0001-5311-4798
Michael R KannUniversity of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID https://orcid.org/0009-0000-6362-2083
William S KremenDepartment of Psychiatry, University of California San Diego, San Diego, California, USA.
Athene LeeDepartment of Psychiatry and Human Behavior, Brown University Warren Alpert Medical School, Providence, Rhode Island, USA.ORCID https://orcid.org/0000-0002-8828-8701
Jairo E MartinezDepartment of Psychological and Brain Sciences, Boston University, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-5888-481X
Arjun V MasurkarDepartment of Neurology, New York University Grossman School of Medicine, New York, New York, USA.
Maia A McLinDepartment of Psychology, Mississippi State University, Mississippi State, Mississippi, USA.
Elisa de Paula França ResendeGlobal Brain Health Institute, University of California San Francisco, San Francisco, California, USA.ORCID https://orcid.org/0000-0002-9758-6452
Zahra RahemiSchool of Nursing, Clemson University, Greenville, South Carolina, USA.ORCID https://orcid.org/0000-0003-1126-2287
Brianca C RenfroDepartment of Psychiatry, Geriatric Center for Cognitive Medicine, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee, USA.ORCID https://orcid.org/0009-0005-7625-2356
Márlon Juliano Romero AlibertiDivision of Geriatrics, University of São Paulo Medical School, São Paulo, Brazil.
Shaina ShagalowDepartment of Neurology, Division of Cognitive Neuroscience, Columbia University Medical Center, New York, New York, USA.ORCID https://orcid.org/0000-0003-1239-9082
Andrea SlachevskyGerosciences Center for Brain Health and Metabolism, Santiago, Chile.ORCID https://orcid.org/0000-0001-6285-3189
Juliana N De Souza TalaricoCollege of Nursing, University of Iowa, Iowa City, Iowa, USA.ORCID https://orcid.org/0000-0001-8820-0725
Jean François TraniInstitute of Public Health, Washington University in St. Louis, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0002-9187-0946
Carol Van HulleDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0002-2288-8819
Leah WaltripDepartment of Psychology, University of Denver, Denver, Colorado, USA.ORCID https://orcid.org/0000-0001-7923-7390
Stephen Ojiambo WanderaDepartment of Population Studies, School of Statistics and Planning, College of Business and Management Sciences, Makerere University, Kampala, Uganda.ORCID https://orcid.org/0000-0002-5617-0274
Charles C WindonDepartment of Neurology, Memory and Aging Center, University of California San Francisco, San Francisco, California, USA.
Mônica Sanches YassudaGerontology, School of Arts, Sciences and Humanities, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-9182-2450
Davide V MorettiIRCSS Istituto Centro San Giovanni di Dio Fatebenefratelli Alzheimer Rehabilitation Operative Unit, Brescia, Italy.
Elizabeth KuhnNormandie University, UNICAEN, INSERM, Caen, France.ORCID https://orcid.org/0000-0002-3744-1155
Elke ButterbrodDepartment of Clinical, Neuro-, and Developmental Psychology, Faculty of Movement and Behavioral Sciences, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Katherine A GiffordDepartment of Anatomy & Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
Sietske A M SikkesDepartment of Clinical, Neuro-, and Developmental Psychology, Faculty of Movement and Behavioral Sciences, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Raphael M CastilhosCognitive and Behavioral Neurology Center, Neurology Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.ORCID https://orcid.org/0000-0002-1905-2084
Rachel NoshenyDepartment of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, California, USA.
Shana D StitesDepartment of Psychiatry and Division of Geriatric Medicine in the Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0003-3994-4343
a collaboration of the Alzheimer's Association International Society to Advance Alzheimer's Research and Therapy Subjective Cognitive Decline and Diversity and Disparities Professional Interest Areas
Funding
TDP-43 Loss-of-Function: Biology to BiomarkersP01AG019724 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jennifer Merrilees · 2002 to 2026
$67.2MResearch Education ComponentP30AG066512 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Mary Sherman Mittelman · 2020 to 2026
$28.4MAn automated machine learning approach to language changes in Alzheimer’s disease and frontotemporal dementia across Latino and English-speaking populationsR01AG075775 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARIA LUISA GORNO TEMPINI, Adolfo Martin Garcia · 2023 to 2026
$7.2MUsing a Health Disparity Research Framework to examine mechanisms linking Obstructive Sleep Apnea with higher Alzheimer’s disease risk in older Blacks/African-AmericansR01AG082278 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI OMONIGHO A MICHAEL Bubu · 2023 to 2026
$6.9MNaturalistic driving as a functional neurobehavioral marker of preclinical and symptomatic Alzheimer diseaseR01AG068183 · NIA · WASHINGTON UNIVERSITY · PI BABULAL, GANESH M · 2020 to 2024
$6.7MUS-South American Initiative for Genetic-Neural-Behavioral Interactions in Human Neurodegenerative ResearchR01AG057234 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Claudia Duran-Aniotz, Agustin M. Ibanez · 2019 to 2026
$6.1MTreatment of OSA on sleep-dependent memory and blood biomarkers in blacksRF1AG083975 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI OMONIGHO A MICHAEL Bubu, Korey Kam · 2023 to 2026
$4.2MThe impact of bilingualism on cognitive reserve/resilience using socio-demographically and linguistically diverse populationsR01AG080469 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Suvarna Alladi, Ganesh M Babulal · 2023 to 2026
$4.0MThe Impact of Depression and Preclinical Alzheimer Disease on Driving Among Older AdultsR01AG067428 · NIA · WASHINGTON UNIVERSITY · PI BABULAL, GANESH M · 2020 to 2024
$4.0MCircadian Disturbance and Dementia in Latin AmericaR01AG083799 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Kun Hu, Agustin M. Ibanez · 2023 to 2026
$3.0MLife-space, isolation, and functional exposome study in preclinical Alzheimer's disease and cognitive environments (LIFESPACE)R01AG089700 · NIA · WASHINGTON UNIVERSITY · PI Ganesh M Babulal · 2025 to 2026
$1.3MThe mediating role of Slow Wave Sleep and Vascular Risk Factors on Alzheimer Disease related disparity between African-Americans and non-Hispanic WhitesK23AG068534 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BUBU, OMONIGHO A MICHAEL · 2021 to 2025
$958kAlzheimer Association ALZ-RWD-26-1466627Alzheimer's Association AARG-21-848397Alzheimer's Association K23AG093166Alzheimer's Association SG-20-725707Alzheimer's Association International Research Grant Program CouncilAlzheimer's Association/Michael J. Fox FoundationAmerican Academy of Sleep Medicine Scientific Review CommitteeAmerican Thoracic Society Conference Program Planning Committeeand NIH-NIA 2P01AG019724and NIH-NIA R01AG057234and NIH-NIA R01AG075775and NIH-NIA R01AG083799and NIH-NIA R01AG21051CARDS - NIHNIA NIH HHS K23 AG065442NIA NIH HHS K23 AG068534NIA NIH HHS K23 AG093166NIA NIH HHS P01 AG019724NIA NIH HHS P30 AG066512NIA NIH HHS R01 AG057234NIA NIH HHS R01 AG067428NIA NIH HHS R01 AG068183NIA NIH HHS R01 AG075775NIA NIH HHS R01 AG080469NIA NIH HHS R01 AG082278NIA NIH HHS R01 AG083799NIA NIH HHS R01 AG089700NIA NIH HHS R13 AG096982NIA NIH HHS RF1 AG083975the Alzheimer's Associationthe National Institutes of Health (NIH)/National Institute on Aging (NIH/NIA) R01AG067428the National Institutes of Health (NIH)/National Institute on Aging (NIH/NIA) R01AG068183the National Institutes of Health (NIH)/National Institute on Aging (NIH/NIA) R01AG080469the National Institutes of Health (NIH)/National Institute on Aging (NIH/NIA) R01AG089700the National Institutes of Health (NIH)/National Institute on Aging (NIH/NIA) R13AG096982the NIH K23AG068534the NIH R01AG082278the NIH RF1AG083975
Abstract
Subjective cognitive decline (SCD) refers to cognitive concerns that may occur with or without objective impairment on standardized testing. Studies suggest that SCD may be an early clinical marker of Alzheimer's disease and related dementias, and that it can predict future objective cognitive decline and progression to dementia. However, the research that supports these conclusions is primarily based on samples with homogeneous socioeconomic and cultural backgrounds. The limited studies in samples with more diverse representations of racial, ethnic, gender, and sexual orientation characteristics show varying SCD prevalence, correlates, and outcomes. Here, we review this literature, focusing on how to apply the findings to advance our understanding of SCD. We further evaluate how our findings inform a roadmap for future research. Overall, we conclude that broader investigations across more diverse populations enhance our understanding of the factors that may differentially contribute to SCD and shape its utility as a clinical metric.
Indexed as
Alzheimer DiseaseCognitive DysfunctionCultural DiversityDementiaHumansAlzheimer's diseaseAlzheimer's disease and related dementiascognitive concernsdiversitysample representationsubjective cognitive decline
Identifiers
What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.