Evidence map›Paper›PMID 42685073›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Rapidly evolving aphid gall effector proteins exhibit saposin-like folds.

Fatema Bhinderwala, Aishwarya Korgaonkar, Kota Gopalakrishna, Thomas C Mathers, Shuji Shigenobu, J Fernando Bazan, Saskia A Hogenhout, Guillermo Calero, Angela M Gronenborn, David L Stern

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Fatema BhinderwalaDepartment of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261.ORCID 0000-0002-3033-8438
Aishwarya KorgaonkarJanelia Research Campus, Janelia Research Campus, HHMI, Ashburn, VA 20147.ORCID 0009-0004-4244-0140
Kota GopalakrishnaJanelia Research Campus, Janelia Research Campus, HHMI, Ashburn, VA 20147.
Thomas C MathersDepartment of Crop Genetics, John Innes Centre, Norwich NR4 7UH, United Kingdom.ORCID 0000-0002-8637-3515
Shuji ShigenobuLaboratory of Evolutionary Genomics, Trans-Scale Biology Center, National Institute for Basic Biology, Myodaiji, Okazaki 444-8585, Japan.ORCID 0000-0003-4640-2323
J Fernando Bazanℏ Bioconsulting llc, Stillwater, MN 55082.ORCID 0000-0002-3645-9935
Saskia A HogenhoutDepartment of Crop Genetics, John Innes Centre, Norwich NR4 7UH, United Kingdom.ORCID 0000-0003-1371-5606
Guillermo CaleroDepartment of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261.ORCID 0000-0003-3730-4676
Angela M GronenbornDepartment of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261.ORCID 0000-0001-9072-3525
David L SternJanelia Research Campus, Janelia Research Campus, HHMI, Ashburn, VA 20147.ORCID 0000-0002-1847-6483

Funding

A Synchrotron Radiation Structural Biology ResourcesP30GM133894 · NIGMS · STANFORD UNIVERSITY · PI Aina E. Cohen, KEITH O HODGSON · 2020 to 2026
$43.3M
NIGMS NIH HHS P30 GM133894
6 · The paper itself

Abstract

Many insects manipulate plants by injecting effector proteins. In one extreme example of this molecular "hijacking,"

Indexed as

AphidsEvolution, MolecularInsect ProteinsSaposinsAmino Acid SequenceAnimalsCrystallography, X-RayModels, MolecularProtein ConformationProtein FoldingSequence AlignmentInsect ProteinsSaposinsAlphafoldeffector proteinsevolutionhost-parasiteprotein structure

Identifiers

PMID42685073
PMCPMC13552887

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.