Evidence map›Paper›PMID 42685608›Full record

ArticleRedox biology2026

Inhibition of 3-mercaptopyruvate sulfurtransferase enhances CD8

Muriel Urwyler, Marietta Margareta Korsos, Eloise Dupuychaffray, Nikita Markov, Kelly Ascenção, Maria Petrosino, Karim Zuhra, Darko Stojkov, Sara Barcos, Jérémie Tachet and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Redox biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Muriel UrwylerInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Switzerland.
Marietta Margareta KorsosInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Switzerland; Institute of Pharmacology, University of Bern, Switzerland.
Eloise DupuychaffrayInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Switzerland; Institute of Pharmacology, University of Bern, Switzerland.
Nikita MarkovInstitute of Pharmacology, University of Bern, Switzerland.
Kelly AscençãoSection of Pharmacology, Department of Oncology, Microbiology and Immunology, University of Fribourg, Switzerland.
Maria PetrosinoSection of Pharmacology, Department of Oncology, Microbiology and Immunology, University of Fribourg, Switzerland.
Karim ZuhraSection of Pharmacology, Department of Oncology, Microbiology and Immunology, University of Fribourg, Switzerland.
Darko StojkovInstitute of Pharmacology, University of Bern, Switzerland.
Sara BarcosTheodor Kocher Institute, University of Bern, Switzerland.
Jérémie TachetInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Switzerland.
Pragallabh PurwarInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Switzerland.
Montserrat AlvarezInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Switzerland.
Aurélien PommierInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Switzerland.
Mohamed Z GadBiochemistry Department, Faculty of Pharmacy and Biotechnology, German University in Cairo (GUC), Cairo, Egypt.
Reham M Abdel-KaderPharmacology and Toxicology Department, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt; University of London at European Universities in Egypt (EUE), New Administrative Capital, Egypt.
Csaba SzaboSection of Pharmacology, Department of Oncology, Microbiology and Immunology, University of Fribourg, Switzerland.
Carole BourquinInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Switzerland; Institute of Pharmacology, University of Bern, Switzerland; Department of Anaesthesiology, Pharmacology, Intensive Care and Emergency Medicine, University of Geneva, Switzerland. Electronic address: carole.bourquin@unibe.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogen sulfide (H

Indexed as

3-mercaptopyruvate sulfurtransferase (3-MST)Hydrogen sulfide (H(2)S)Immune checkpoint inhibitionRenal cell cancerTumor immunotherapy

Identifiers

PMID42685608
PMCPMC13570292

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.