Evidence map›Paper›PMID 42686995›Full record

ArticleMolecular psychiatry2026

Striatal dopaminergic function and cortical functional connectivity in 22q11.2 deletion syndrome: an integrative multimodal

Valentina Mancini, Maria Rogdaki, Sameer Jauhar, Manuela Moretto, Mattia Veronese, Federico Turkheimer, Oliver D Howes, Robert A McCutcheon

Abstract read
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In one paragraph

Article in Molecular psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Valentina Mancini *Department of Psychiatry, University of Oxford, Oxford, UK. valentina.mancini@ndcn.ox.ac.uk.ORCID http://orcid.org/0000-0003-4411-896X
Maria Rogdaki *Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0000-0003-2685-1789
Sameer JauharDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0000-0002-3878-3659
Manuela MorettoCentre for Neuroimaging Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College, London, UK.
Mattia VeroneseCentre for Neuroimaging Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College, London, UK.ORCID http://orcid.org/0000-0003-3562-0683
Federico TurkheimerCentre for Neuroimaging Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College, London, UK.ORCID http://orcid.org/0000-0002-3766-3815
Oliver D HowesDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0000-0002-2928-1972
Robert A McCutcheonDepartment of Psychiatry, University of Oxford, Oxford, UK. robert.mccutcheon@psych.ox.ac.uk.ORCID http://orcid.org/0000-0003-1102-2566

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) P500PM_217669Wellcome Trust (Wellcome) 224625/Z/21/Z
6 · The paper itself

Abstract

Dopaminergic signalling is critical for regulating large-scale brain network dynamics and is implicated in the pathophysiology of psychotic disorders. 22q11.2 deletion syndrome (22q11DS), a high-penetrance genetic risk factor for schizophrenia, is associated with both dopaminergic alterations and disruptions in functional connectivity (FC), yet the degree to which these separate people with 22q11DS from healthy controls and their inter-relationship remains unclear. Eighteen individuals with 22q11DS (no history of psychosis or antipsychotic use) and 22 controls underwent [

Identifiers

What Socratic holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.