ArticleArXiv2026
A Novel Differential Pathlength Factor Model for Near-Infrared Diffuse Optical Imaging.
Article in ArXiv, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
3 authors.
Funding
Abstract
Continuous-wave near-infrared diffuse optical imaging (DOI) relies on accurate differential pathlength factors (DPFs) for quantitative chromophore estimation. Existing DPF definitions inherit formulation-dependent limitations that can introduce large errors in modified Beer-Lambert law (MBLL) analyses and associated inverse estimations. We propose two new DPF formulations: an MBLL-based formulation derived directly from photon-transport statistics and an experimentally practical inverse-distance model that closely reproduces the results of the more rigorous MBLL-based formulation. These models are derived based on extensive Monte Carlo simulations whereby we exclusively assign the source-detector-separation dependence of optical density (OD) to the Beer-Lambert term for a given object geometry, boundary configuration, and measurement setup. The additive term
Identifiers
42687887PMC13532703What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.