ArticleResearch square2026
Conserved catalytic motifs encode enzyme-like supramolecular peptide assemblies.
Liam R Marshall, Sagar Bhattacharya, Leonardo F Serafim, Parth Rathee, Malitha C Dickwella Widanage, Prerana Dash, Yang Li, Ho Yee Joyce Fung, Souvik Panda Mahapatra, Marianne L Jensen and 4 more
Abstract readPreprint
In one paragraphArticle in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Leonardo F SerafimDepartment of Chemistry, University of Miami; Coral Gable, FL, USA.
Parth RatheeDepartment of Chemistry, University of Miami; Coral Gable, FL, USA.
Malitha C Dickwella WidanageDepartment of Chemistry, Michigan State University; East Lansing, MI, USA.
Prerana DashDepartment of Chemistry and Biochemistry; Baylor University, Waco, TX, USA.
Ho Yee Joyce FungDepartment of Biophysics, University of Texas Southwestern Medical Center; Dallas, TX, USA.ORCID 0000-0002-0502-1957 Souvik Panda MahapatraDepartment of Chemistry and Biochemistry; Baylor University, Waco, TX, USA.
Marianne L JensenDepartment of Chemistry, University of Copenhagen; Copenhagen, Denmark.
Lars HemmingsenDepartment of Chemistry, University of Copenhagen; Copenhagen, Denmark.
Rajeev PrabhakarDepartment of Chemistry, University of Miami; Coral Gable, FL, USA.
Funding
Pacific Northwest Center for Cryo-EM: Equipment SupplementR24GM154185 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI James E Evans, CLAUDIA SUSANA LOPEZ · 2024 to 2026
$21.5MUnderstanding Evolution of Protein Function Through Design.R35GM119634 · NIGMS · SYRACUSE UNIVERSITY · PI KORENDOVYCH, IVAN V · 2016 to 2025
$4.3MRevealing the Cell Wall Organization of Fungal Pathogens and Structural Responses to Antifungal Drugs Using Cellular Solid-State NMRR01AI173270 · NIAID · MICHIGAN STATE UNIVERSITY · PI Tuo Wang · 2023 to 2026
$1.5MNIAID NIH HHS R01 AI173270NIGMS NIH HHS R24 GM154185NIGMS NIH HHS R35 GM119634
6 · The paper itselfAbstract
A seven-residue fragment derived from the active-site region of carbonic anhydrase spontaneously forms Zn
Identifiers
PMID42688037
PMCPMC13533019
What Socratic holds
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