Evidence map›Paper›PMID 42688487›Full record

ArticleFrontiers in cell and developmental biology2026

Measles virus reprograms CD4

Maria Fernanda Grijalva Yépez, Yann Loïc Cordes, Agnes Fekete, Fabian Schumacher, Burkhard Kleuser, Elita Avota

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria Fernanda Grijalva YépezInstitute for Virology and Immunobiology, University of Wuerzburg, Wuerzburg, Germany.
Yann Loïc CordesInstitute for Virology and Immunobiology, University of Wuerzburg, Wuerzburg, Germany.
Agnes FeketePharmaceutical Biology, Julius-von-Sachs-Institute, Biocenter, University of Wuerzburg, Wuerzburg, Germany.
Fabian SchumacherInstitute of Pharmacy, Department of Pharmacology, Freie Universität Berlin, Berlin, Germany.
Burkhard KleuserInstitute of Pharmacy, Department of Pharmacology, Freie Universität Berlin, Berlin, Germany.
Elita AvotaInstitute for Virology and Immunobiology, University of Wuerzburg, Wuerzburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: CD150-positive (CD150 Methods and Results: In this study, a comprehensive lipidomic analysis of MV-infected primary CD4 Discussion: Mechanistically, we demonstrate that MV glycoprotein-mediated membrane fusion, essential for viral entry and cell-to-cell spread, requires glucosylceramide synthase (GCS) activity and is further promoted by plasma membrane triacylglycerol content. Collectively, these findings highlight the essential role of MV-modulated triacylglycerol and sphingolipid metabolism in viral entry, dissemination, and intracellular replication within CD4

Indexed as

CD4+CD150+ T cellceramide (CER)dihydroceramide (dhCer)hexosylceramide (HexCer)measles virus (MV)signaling lymphocytic activation molecule family member 1 (SLAMF1/CD150)sphingolipidstriacylglycerol (TG)

Identifiers

PMID42688487
PMCPMC13534112

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.