Evidence map›Paper›PMID 42689549›Full record

ArticleeLife2026

Zahra Seraj, Ximena Zottig, ChunYing Huang, Anna B Loveland, Stephen Diggs, Emily Sholi, Nikolaus Grigorieff, Andrei A Korostelev

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. eLife · 2026
    Article
  2. Structural basis for emetine inhibition of ribosome translocation inbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Structural basis for non-AUG translation regulation by 5MPs.bioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

  • Update of
    2025
5 · Who and what money

Authors and funding

8 authors.

Zahra SerajRNA Therapeutics Institute, UMass Chan Medical School, Worcester, United States.ORCID https://orcid.org/0000-0003-2405-6212
Ximena ZottigRNA Therapeutics Institute, UMass Chan Medical School, Worcester, United States.ORCID https://orcid.org/0000-0002-2344-5163
ChunYing HuangRNA Therapeutics Institute, UMass Chan Medical School, Worcester, United States.ORCID https://orcid.org/0000-0001-8728-5261
Anna B LovelandRNA Therapeutics Institute, UMass Chan Medical School, Worcester, United States.ORCID https://orcid.org/0000-0001-9172-7747
Stephen DiggsRNA Therapeutics Institute, UMass Chan Medical School, Worcester, United States.ORCID https://orcid.org/0000-0003-0312-9224
Emily SholiRNA Therapeutics Institute, UMass Chan Medical School, Worcester, United States.ORCID https://orcid.org/0000-0003-4609-4607
Nikolaus GrigorieffRNA Therapeutics Institute, UMass Chan Medical School, Worcester, United States.ORCID https://orcid.org/0000-0002-1506-909X
Andrei A KorostelevRNA Therapeutics Institute, UMass Chan Medical School, Worcester, United States.ORCID https://orcid.org/0000-0003-1588-717X

Funding

CHEETAH Center for the Structural Biology of HIV Infection, Restriction, and Viral DynamicsU54AI170856 · NIAID · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI WALTHER H MOTHES · 2022 to 2026
$34.4M
Translational Control: Discovery and MechanismsR35GM127094 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Andrei Korostelev · 2018 to 2026
$5.5M
NIAID NIH HHS U54 AI170856NIGMS NIH HHS R35 GM127094NIH HHS R35GM127094US National Institutes of Health CHEETAH U54AI170856
6 · The paper itself

Abstract

Cryogenic electron microscopy (cryo-EM) made impressive progress in resolving cellular macromolecules and their detailed interactions. Single-particle cryo-EM traditionally relies on purified macromolecules and lacks the complexity of cellular environments, whereas

Indexed as

Cryoelectron MicroscopyPeptide Elongation Factor 2Ribosome Subunits, Large, EukaryoticAnimalsCell LineHumansRabbitsReticulocytesRibosomesPeptide Elongation Factor 2H. sapienshumanmammalianmolecular biophysicsOryctolagus cuniculusrabbitRRLstructural biology

Identifiers

PMID42689549
PMCPMC13541302

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.