Evidence map›Paper›PMID 42690122›Full record

ArticleJournal of comparative effectiveness research2026

US population-level model of clinical impact of lorlatinib treatment on ALK+ metastatic non-small cell lung cancer outcomes.

Adam Kasle, Devin Abrahami, David Veenstra, Robert Morlock, Priya Ramachandran, Lindsay Stansfield, Raymond Mak

Abstract read
In one paragraph

Article in Journal of comparative effectiveness research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adam KasleCurta, Inc., Seattle, WA 98104, USA.ORCID 0000-0003-3468-8184
Devin AbrahamiHTA Value & Evidence, Oncology, Pfizer Inc., New York, NY 10001, USA.ORCID 0000-0001-5269-2377
David VeenstraCurta, Inc., Seattle, WA 98104, USA.
Robert MorlockYourCareChoice, Ann Arbor, MI 48104, USA.ORCID 0000-0002-8723-2562
Priya RamachandranPfizer Inc., New York, NY 10001, USA.
Lindsay StansfieldPfizer Inc., New York, NY 10001, USA.
Raymond MakMass General Brigham, Boston, MA 02199, USA.ORCID 0000-0002-8754-0565

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CarbazolesCarcinoma, Non-Small-Cell LungLactams, MacrocyclicLung NeoplasmsProtein Kinase InhibitorsPyrazolesAminopyridinesAnaplastic Lymphoma KinaseBrain NeoplasmsComparative Effectiveness ResearchFemaleHumansLactamsMaleMiddle AgedPiperidinesalectinibALK protein, humanAminopyridinesAnaplastic Lymphoma KinaseCarbazolesLactamsLactams, MacrocycliclorlatinibPiperidinesProtein Kinase InhibitorsPyrazolesALK-positive non-small cell lung cancerbrain metastasesmatch-adjusted indirect comparisonnumber needed to treatpartitioned survival modelpopulation impact modelquality-adjusted life years

Identifiers

PMID42690122
PMCPMC13648051

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.