ReviewMolecular biology reports2026
Oocyte quality in endometriosis-associated infertility: a narrative analysis of mechanisms and therapeutic options.
Review in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endometriosis is a challenging gynaecological condition that can lead to infertility. This unique narrative review summarises the impact of endometriosis, focusing on oocyte quality, its subcellular and molecular mechanisms, clinical effects, and therapeutic options. The disease is associated with a hostile follicular microenvironment caused by inflammation, oxidative stress, granulosa and cumulus cell dysfunction, and hormonal dysregulation. It further leads to spindle disorders, mitochondrial DNA breakdown, and delayed cytoplasmic maturation. Women with stage III-IV endometriosis have low ovarian reserve, fewer retrieved and matured (MII) oocytes, and lower fertilisation and blastocyst development rates, resulting in worse cumulative pregnancy outcomes. However, when good-quality embryos are transferred, implantation and live birth rates are often similar to those of controls, suggesting that the problem is primarily oocyte-driven rather than endometrium-related. Therapeutic options include lifestyle modifications with a healthy diet, yoga, exercise, adequate sleep, and stress management, in addition to individualised assisted reproductive technology (ART) treatments, to enhance prognosis, though with sub-optimal proven mechanisms.
Indexed as
Identifiers
42690563What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.