Evidence map›Paper›PMID 42694243›Full record

ArticleNPJ dementia2026

Blood-based biomarkers of Alzheimer's disease and neurodegeneration in an indigenous African cohort using both Simoa and NULISA platforms.

Tolulope Akinyemi, Ilaria Pola, Kubra Tan, Oladotun Olalusi, Joseph Yaria, Gabriel Ogunde, Wiebke Traichel, Nesrine Rahmouni, Olabode Oguntiloye, Ayotomiwa Fagbemi and 19 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ dementia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

29 authors.

Tolulope Akinyemi *Departments of Biological and Chemical Sciences, Faculty of Natural and Applied Science, Lead City University, Ibadan, Nigeria.
Ilaria Pola *Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
Kubra TanDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
Oladotun OlalusiNeuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Joseph YariaDepartment of Neurology, University College Hospital, Ibadan, Oyo, Nigeria.
Gabriel OgundeNeuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Wiebke TraichelDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
Nesrine RahmouniDiscipline of Medical Gerontology, School of Medicine, Trinity College Dublin, Dublin, Ireland.
Olabode OguntiloyeDepartment of Neurology, University College Hospital, Ibadan, Oyo, Nigeria.
Ayotomiwa FagbemiDepartment of Neurology, University College Hospital, Ibadan, Oyo, Nigeria.
Eniola CadmusDepartment of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Quebec, QC Canada.
Femi PopoolaDepartment of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Quebec, QC Canada.
Joseph TherriaultDiscipline of Medical Gerontology, School of Medicine, Trinity College Dublin, Dublin, Ireland.
Mayowa OgunronbiNeuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Dorcas OlujobiNeuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Olaoluwa FamuyiwaNeuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Joshua AkinyemiNeuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Tharick PascoalDepartment of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Mayowa OwolabiNeuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Pedro Rosa-NetoDiscipline of Medical Gerontology, School of Medicine, Trinity College Dublin, Dublin, Ireland.
Chinedu T Udeh-MomohTrinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.
Olusola LadokunDepartments of Biological and Chemical Sciences, Faculty of Natural and Applied Science, Lead City University, Ibadan, Nigeria.
Roman Romero-OrtunoClinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
Adesola OgunniyiNeuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Brian LawlorDepartment of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.
Rajesh KalariaNeuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Henrik ZetterbergDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
Andrea L BenedetDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
Rufus AkinyemiNeuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.

Funding

Head-to-head comparisons of high-performance plasma phospho-tau epitopes for the detection of Alzheimer's diseaseR01AG075336 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Tharick Pascoal · 2022 to 2026
$3.7M
NIA NIH HHS R01 AG075336
6 · The paper itself

Abstract

In low- and middle-income countries, Alzheimer's disease (AD) constitutes a growing public health burden. However, AD biomarkers research remains underrepresented in African populations. This study assesses core biomarkers of AD and their relevance in the African context as potential aid in clinical diagnosis. Nigerian older adults from VALIANT cohort (

Indexed as

BiomarkersDiseasesMedical researchNeurologyNeuroscience

Identifiers

PMID42694243
PMCPMC13538047

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.